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Production of Quorum Sensing Inhibitors in Growing Onion Bulbs Infected with Pseudomonas aeruginosa E (HQ324110)
Joint Authors
Bashandy, Shymaa R.
Abd-Alla, Mohamed H.
Source
Issue
Vol. 2012, Issue 2012 (31 Dec. 2012), pp.1-7, 7 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2012-01-05
Country of Publication
Egypt
No. of Pages
7
Main Subjects
Abstract EN
Eighteen organic compounds were present in growing onion bulbs cultivar Giza 6 infected with P.
aeruginosa, but only fourteen of them are present in dry infected onion bulbs; however, four compounds were missing in dry onion.
The missing compounds in dry infected onion bulbs are pantolactone, 4,5-dihydro-4,5-dimethylfuran-2(3H)-one, myristic acid, and linoleic acid.
All of them were detected in growing onion (living cell) during Pseudomonas aeruginosa infection, and it is hypothesized that it may be produced by plants and act as defence system.
Pantolactone and myristic acid were selected to explore their effects on growth and virulence factors of Pseudomonas aeruginosa.
Exogenous application of pantolactone and myristic acid significantly inhibited pyocyanin production, protease, and lipase and polygalacturonase activity but did not have any significant effects on bacterial growth.
The inhibition of virulence factors without reduction in bacterial growth may be providing strong support that these chemical molecules are general quorum sensing inhibitors than an antibacterial effect.
Disruption of quorum sensing of pathogen indicates that this new approach has potential in fighting bacterial infections in human and plants.
American Psychological Association (APA)
Abd-Alla, Mohamed H.& Bashandy, Shymaa R.. 2012. Production of Quorum Sensing Inhibitors in Growing Onion Bulbs Infected with Pseudomonas aeruginosa E (HQ324110). ISRN Microbiology،Vol. 2012, no. 2012, pp.1-7.
https://search.emarefa.net/detail/BIM-450774
Modern Language Association (MLA)
Abd-Alla, Mohamed H.& Bashandy, Shymaa R.. Production of Quorum Sensing Inhibitors in Growing Onion Bulbs Infected with Pseudomonas aeruginosa E (HQ324110). ISRN Microbiology No. 2012 (2012), pp.1-7.
https://search.emarefa.net/detail/BIM-450774
American Medical Association (AMA)
Abd-Alla, Mohamed H.& Bashandy, Shymaa R.. Production of Quorum Sensing Inhibitors in Growing Onion Bulbs Infected with Pseudomonas aeruginosa E (HQ324110). ISRN Microbiology. 2012. Vol. 2012, no. 2012, pp.1-7.
https://search.emarefa.net/detail/BIM-450774
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-450774