Effects of Statins on Cardiorenal Syndrome
Joint Authors
Matsumoto, Toshio
Yagi, Shusuke
Sata, Masataka
Akaike, Masashi
Ikeda, Yasumasa
Aihara, Ken Ichi
Source
International Journal of Vascular Medicine
Issue
Vol. 2012, Issue 2012 (31 Dec. 2012), pp.1-7, 7 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2012-06-26
Country of Publication
Egypt
No. of Pages
7
Main Subjects
Abstract EN
Cardiovascular disease and renal disease have a close relationship that forms a vicious cycle as a cardiorenal syndrome (CRS).
Oxidative stress, endothelial dysfunction, and vascular inflammation could be therapeutic targets when the renin-angiotensin-aldosterone system is activated by accumulation of conventional cardiovascular risk factors; however, a strategy for management of CRS has not been established yet.
Statins, HMG-CoA reductase inhibitors, have not only cholesterol-lowering effects but also pleiotropic effects on cardiovascular systems, including anti-inflammatory and antioxidant effects and improvement of nitric oxide bioavailability.
Since recent studies have indicated that statins have beneficial effects on chronic kidney disease and heart failure as well as coronary artery disease in cholesterol-lowering-dependent/independent manners, treatment with statins might be a successful strategy for preventing deterioration of CRS.
American Psychological Association (APA)
Yagi, Shusuke& Aihara, Ken Ichi& Ikeda, Yasumasa& Akaike, Masashi& Sata, Masataka& Matsumoto, Toshio. 2012. Effects of Statins on Cardiorenal Syndrome. International Journal of Vascular Medicine،Vol. 2012, no. 2012, pp.1-7.
https://search.emarefa.net/detail/BIM-450836
Modern Language Association (MLA)
Yagi, Shusuke…[et al.]. Effects of Statins on Cardiorenal Syndrome. International Journal of Vascular Medicine No. 2012 (2012), pp.1-7.
https://search.emarefa.net/detail/BIM-450836
American Medical Association (AMA)
Yagi, Shusuke& Aihara, Ken Ichi& Ikeda, Yasumasa& Akaike, Masashi& Sata, Masataka& Matsumoto, Toshio. Effects of Statins on Cardiorenal Syndrome. International Journal of Vascular Medicine. 2012. Vol. 2012, no. 2012, pp.1-7.
https://search.emarefa.net/detail/BIM-450836
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-450836