Nephrotic Syndrome Secondary to Proliferative Glomerulonephritis with Monoclonal Immunoglobulin Deposits of Lambda Light Chain
Joint Authors
Yun, Seongseok
Walker, Courtney N.
Braunhut, Beth L.
Bhati, Waheed
Sussman, Amy N.
Anwer, Faiz
Source
Issue
Vol. 2014, Issue 2014 (31 Dec. 2014), pp.1-6, 6 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2014-07-22
Country of Publication
Egypt
No. of Pages
6
Main Subjects
Abstract EN
We describe a rare case of a 46-year-old woman with history of refractory nephrotic syndrome and hypertension who presented with worsening proteinuria and kidney function.
Work-up for both autoimmune and infectious diseases and hematologic malignancies including multiple myeloma were negative.
Kidney biopsy demonstrated glomerular sclerotic change with lambda light chain deposits in the subendothelial space, which is consistent with proliferative glomerulonephritis with monoclonal immunoglobulin deposit (PGNMID).
The patient was treated with bortezomib and dexamethasone without clinical improvement and eventually became hemodialysis dependent.
American Psychological Association (APA)
Yun, Seongseok& Braunhut, Beth L.& Walker, Courtney N.& Bhati, Waheed& Sussman, Amy N.& Anwer, Faiz. 2014. Nephrotic Syndrome Secondary to Proliferative Glomerulonephritis with Monoclonal Immunoglobulin Deposits of Lambda Light Chain. Case Reports in Nephrology،Vol. 2014, no. 2014, pp.1-6.
https://search.emarefa.net/detail/BIM-451033
Modern Language Association (MLA)
Yun, Seongseok…[et al.]. Nephrotic Syndrome Secondary to Proliferative Glomerulonephritis with Monoclonal Immunoglobulin Deposits of Lambda Light Chain. Case Reports in Nephrology No. 2014 (2014), pp.1-6.
https://search.emarefa.net/detail/BIM-451033
American Medical Association (AMA)
Yun, Seongseok& Braunhut, Beth L.& Walker, Courtney N.& Bhati, Waheed& Sussman, Amy N.& Anwer, Faiz. Nephrotic Syndrome Secondary to Proliferative Glomerulonephritis with Monoclonal Immunoglobulin Deposits of Lambda Light Chain. Case Reports in Nephrology. 2014. Vol. 2014, no. 2014, pp.1-6.
https://search.emarefa.net/detail/BIM-451033
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-451033