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Epstein-Barr-Virus-Positive B-Cell Lymphoma of Recipient Origin Despite of the Elimination of Clonally EBV-Infected T Cells by Allogeneic Stem Cell Transplantation in a Patient with Chronic Active EBV Infection
Author
Source
Case Reports in Transplantation
Issue
Vol. 2012, Issue 2012 (31 Dec. 2012), pp.1-5, 5 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2012-06-13
Country of Publication
Egypt
No. of Pages
5
Main Subjects
Abstract EN
A 20-year-old patient with chronic active EBV infection (CAEBV) received peripheral blood stem cell transplantation (PBSCT) from HLA-one-locus-mismatched mother.
Although EB-virus-infected T cells were eliminated after PBSCT, she developed EB-virus-positive B-cell lymphoma of recipient origin in the brain.
By reducing the immunosuppressive therapy, the initial lesion disappeared.
However, another lesion in the opposite lateral brain appeared later and was resistant to further reduction of immunosuppressive therapy.
EBV-DNA was persistently negative after PBSCT in the peripheral blood.
This case is suggestive in management of EBV reactivation after SCT and understanding alloimmune response to EBV.
American Psychological Association (APA)
Nagasawa, Masayuki. 2012. Epstein-Barr-Virus-Positive B-Cell Lymphoma of Recipient Origin Despite of the Elimination of Clonally EBV-Infected T Cells by Allogeneic Stem Cell Transplantation in a Patient with Chronic Active EBV Infection. Case Reports in Transplantation،Vol. 2012, no. 2012, pp.1-5.
https://search.emarefa.net/detail/BIM-451047
Modern Language Association (MLA)
Nagasawa, Masayuki. Epstein-Barr-Virus-Positive B-Cell Lymphoma of Recipient Origin Despite of the Elimination of Clonally EBV-Infected T Cells by Allogeneic Stem Cell Transplantation in a Patient with Chronic Active EBV Infection. Case Reports in Transplantation No. 2012 (2012), pp.1-5.
https://search.emarefa.net/detail/BIM-451047
American Medical Association (AMA)
Nagasawa, Masayuki. Epstein-Barr-Virus-Positive B-Cell Lymphoma of Recipient Origin Despite of the Elimination of Clonally EBV-Infected T Cells by Allogeneic Stem Cell Transplantation in a Patient with Chronic Active EBV Infection. Case Reports in Transplantation. 2012. Vol. 2012, no. 2012, pp.1-5.
https://search.emarefa.net/detail/BIM-451047
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-451047