A Rationale for the Use of F18-FDG PETCT in Fever and Inflammation of Unknown Origin
Joint Authors
van Eck-Smit, Berthe L. F.
Bennink, R. J.
Balink, H.
Verberne, Hein J.
Source
International Journal of Molecular Imaging
Issue
Vol. 2012, Issue 2012 (31 Dec. 2012), pp.1-12, 12 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2012-12-17
Country of Publication
Egypt
No. of Pages
12
Main Subjects
Abstract EN
This review focuses on the diagnostic value of hybrid F18-FDG Positron Emission Tomography/Computerized tomography (PET/CT) in fever of unknown origin (FUO) and inflammation of unknown origin (IUO).
Due to the wide range of possible causes both FUO and IUO remain a clinical challenge for both patients and physicians.
In addition, the aetiology of IUO shows the same variation in diseases as the FUO spectrum and probably requires the same diagnostic approach as FUO.
There are numerous historically used diagnostic approaches incorporating invasive and non-invasive, and imaging techniques, all with relative high specificity but limited sensitivity.
This hampers the generalization of these diagnostic approaches.
However, recently published reports show that F18-FDG PET/CT in FUO and IUO has a high sensitivity and a relative non-specificity for malignancy, infection and inflammation.
This makes F18-FDG PET/CT an ideal diagnostic tool to start the diagnostic process and to guide subsequent focused diagnostic approaches with higher specificity.
In addition, F18-FDG PET/CT has a relative high negative predictive value.
Therefore F18 FDG PET/CT should be incorporated in the routine diagnostic work-up of patients with FUO and IUO, preferably at an early stage in the diagnostic process.
American Psychological Association (APA)
Balink, H.& Verberne, Hein J.& Bennink, R. J.& van Eck-Smit, Berthe L. F.. 2012. A Rationale for the Use of F18-FDG PETCT in Fever and Inflammation of Unknown Origin. International Journal of Molecular Imaging،Vol. 2012, no. 2012, pp.1-12.
https://search.emarefa.net/detail/BIM-451085
Modern Language Association (MLA)
Balink, H.…[et al.]. A Rationale for the Use of F18-FDG PETCT in Fever and Inflammation of Unknown Origin. International Journal of Molecular Imaging No. 2012 (2012), pp.1-12.
https://search.emarefa.net/detail/BIM-451085
American Medical Association (AMA)
Balink, H.& Verberne, Hein J.& Bennink, R. J.& van Eck-Smit, Berthe L. F.. A Rationale for the Use of F18-FDG PETCT in Fever and Inflammation of Unknown Origin. International Journal of Molecular Imaging. 2012. Vol. 2012, no. 2012, pp.1-12.
https://search.emarefa.net/detail/BIM-451085
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-451085