Reconstruction of Mandibular Defects Using Bone Morphogenic Protein : Can Growth Factors Replace the Need for Autologous Bone Grafts? A Systematic Review of the Literature
Joint Authors
Herford, Alan S.
Tandon, Rahul
Stoffella, Enrico
Source
Issue
Vol. 2011, Issue 2011 (31 Dec. 2011), pp.1-7, 7 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2011-11-24
Country of Publication
Egypt
No. of Pages
7
Main Subjects
Abstract EN
Autogenous bone is still considered the “gold standard” of regenerative and reconstructive procedures involving mandibular defects.
However, harvesting of this material can lead to many complications like increasing morbidity, expanding of the surgical time, and incomplete healing of the donor site.
In the last few years many authors looked for the development of effective reconstruction procedures using osteoinductive factors without the need for conventional bone grafting.
The first-in-human study involving the use of Bone Morphongenic Proteins (rhBMP) for mandibular reconstruction was performed in 2001 by Moghadam.
Only few articles have been reported in the literature since then.
The purpose of this study was to search and analyze the literature involving the use of rhBMP for reconstruction of mandibular defects.
In all the studies reported, authors agree that the use of grown factors may represent the future of regenerative procedures with more research necessary for confirmation.
American Psychological Association (APA)
Herford, Alan S.& Stoffella, Enrico& Tandon, Rahul. 2011. Reconstruction of Mandibular Defects Using Bone Morphogenic Protein : Can Growth Factors Replace the Need for Autologous Bone Grafts? A Systematic Review of the Literature. Plastic Surgery International،Vol. 2011, no. 2011, pp.1-7.
https://search.emarefa.net/detail/BIM-451146
Modern Language Association (MLA)
Herford, Alan S.…[et al.]. Reconstruction of Mandibular Defects Using Bone Morphogenic Protein : Can Growth Factors Replace the Need for Autologous Bone Grafts? A Systematic Review of the Literature. Plastic Surgery International No. 2011 (2011), pp.1-7.
https://search.emarefa.net/detail/BIM-451146
American Medical Association (AMA)
Herford, Alan S.& Stoffella, Enrico& Tandon, Rahul. Reconstruction of Mandibular Defects Using Bone Morphogenic Protein : Can Growth Factors Replace the Need for Autologous Bone Grafts? A Systematic Review of the Literature. Plastic Surgery International. 2011. Vol. 2011, no. 2011, pp.1-7.
https://search.emarefa.net/detail/BIM-451146
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-451146