Resurrecting Brinley Plots for a Novel Use : Meta-Analyses of Functional Brain Imaging Data in Older Adults
Joint Authors
Laurienti, Paul J.
Peiffer, Ann M.
Maldjian, Joseph A.
Source
International Journal of Biomedical Imaging
Issue
Vol. 2008, Issue 2008 (31 Dec. 2008), pp.1-7, 7 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2007-10-03
Country of Publication
Egypt
No. of Pages
7
Main Subjects
Abstract EN
By plotting response times of young and older adults across a variety of tasks, Brinley spurred investigation and debate into the theory of general cognitive slowing.
Though controversial, Brinley plots can assess between-task differences, the impact of increasing task demand, and the relationship between responses in two groups of subjects.
Since a relationship exists between response times and the blood-oxygen level dependent (BOLD) signal of functional MRI (fMRI), Brinley's plotting method could be applied as a meta-analysis tool in fMRI studies of aging.
Here, fledgling “Peiffer plots” are discussed for their potential impact on understanding general cognitive brain activity in aging.
Preliminary results suggest that general cognitive slowing may be localized at the sensorimotor transformation in the precentral gyrus.
Although this meta-analysis method is naturally used with imaging studies of aging, theoretically it may be applied to other study pairs (e.g., schizophrenic versus normal) or imaging datasets (e.g., PET).
American Psychological Association (APA)
Peiffer, Ann M.& Maldjian, Joseph A.& Laurienti, Paul J.. 2007. Resurrecting Brinley Plots for a Novel Use : Meta-Analyses of Functional Brain Imaging Data in Older Adults. International Journal of Biomedical Imaging،Vol. 2008, no. 2008, pp.1-7.
https://search.emarefa.net/detail/BIM-451184
Modern Language Association (MLA)
Peiffer, Ann M.…[et al.]. Resurrecting Brinley Plots for a Novel Use : Meta-Analyses of Functional Brain Imaging Data in Older Adults. International Journal of Biomedical Imaging No. 2008 (2008), pp.1-7.
https://search.emarefa.net/detail/BIM-451184
American Medical Association (AMA)
Peiffer, Ann M.& Maldjian, Joseph A.& Laurienti, Paul J.. Resurrecting Brinley Plots for a Novel Use : Meta-Analyses of Functional Brain Imaging Data in Older Adults. International Journal of Biomedical Imaging. 2007. Vol. 2008, no. 2008, pp.1-7.
https://search.emarefa.net/detail/BIM-451184
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-451184