![](/images/graphics-bg.png)
The Role of Somatostatin Receptor Scintigraphy on the Diagnosis of Desmoid Tumors
Joint Authors
Leithner, Andreas
Sadoghi, Patrick
Weger, Christian
Aigner, Reingard
Friesenbichler, Joerg
Molcan, Anja
Liegl-Atzwanger, Bernadette
Maurer-Ertl, Werner
Source
Issue
Vol. 2012, Issue 2012 (31 Dec. 2012), pp.1-6, 6 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2012-05-31
Country of Publication
Egypt
No. of Pages
6
Main Subjects
Abstract EN
Background.
Magnetic resonance imaging is considered as imaging modality of choice in diagnosis of desmoid tumors, though even this technique can lack the ability to distinguish aggressive fibromatosis from other benign or malignant soft tissue tumors.
The aim of this study was to investigate if desmoid tumors would show an adequate tracer uptake in somatostatin receptor scintigraphy and moreover to correlate these results with immunohistochemical staining.
Patients and Methods.
Thirteen patients with desmoid tumors were examined with somatostatin receptor scintigraphy.
Additionally, seven of these patients have been tested for the immunohistochemical expression of somatostatin receptor subtype 2A.
The results of somatostatin receptor scintigraphy and the results of immunohistochemical staining (somatostatin receptor subtype 2A) were evaluated and correlated.
Results.
Somatostatin receptor scintigraphy revealed that eight of 13 affected patients (62%) showed an enhanced tracer uptake.
On the other hand, the correlation between the results of somatostatin receptor scintigraphy and immunohistochemical investigations was poor (two out of seven cases).
Conclusion.
The current study demonstrated that desmoid tumors frequently express somatostatin receptor subtype 2, while immunohistochemical investigations did not correlate with these findings.
This may likely be due to lack of standardization of this technique and also due to heterogeneous receptor distribution within the tumors.
American Psychological Association (APA)
Friesenbichler, Joerg& Molcan, Anja& Aigner, Reingard& Sadoghi, Patrick& Liegl-Atzwanger, Bernadette& Maurer-Ertl, Werner…[et al.]. 2012. The Role of Somatostatin Receptor Scintigraphy on the Diagnosis of Desmoid Tumors. ISRN Oncology،Vol. 2012, no. 2012, pp.1-6.
https://search.emarefa.net/detail/BIM-451238
Modern Language Association (MLA)
Friesenbichler, Joerg…[et al.]. The Role of Somatostatin Receptor Scintigraphy on the Diagnosis of Desmoid Tumors. ISRN Oncology No. 2012 (2012), pp.1-6.
https://search.emarefa.net/detail/BIM-451238
American Medical Association (AMA)
Friesenbichler, Joerg& Molcan, Anja& Aigner, Reingard& Sadoghi, Patrick& Liegl-Atzwanger, Bernadette& Maurer-Ertl, Werner…[et al.]. The Role of Somatostatin Receptor Scintigraphy on the Diagnosis of Desmoid Tumors. ISRN Oncology. 2012. Vol. 2012, no. 2012, pp.1-6.
https://search.emarefa.net/detail/BIM-451238
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-451238