The Optimal First-Line Therapy of Helicobacter pylori Infection in Year 2012
Joint Authors
Wang, Sophie S. W.
Hsieh, Ming-Chia
Kuo, Fu-Chen
Chen, Tun-Chieh
Liu, Chung-Jung
Hu, Huang-Ming
Hou, Ming-Feng
Kuo, Chao-Hung
Wu, Deng-Chyang
Source
Gastroenterology Research and Practice
Issue
Vol. 2012, Issue 2012 (31 Dec. 2012), pp.1-8, 8 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2012-06-27
Country of Publication
Egypt
No. of Pages
8
Main Subjects
Abstract EN
This paper reviews the literature about first-line therapies for H.
pylori infection in recent years.
First-line therapies are facing a challenge because of increasing treatment failure due to elevated antibiotics resistance.
Several new treatment strategies that recently emerged to overcome antibiotic resistance have been surveyed.
Alternative first-line therapies include bismuth-containing quadruple therapy, sequential therapy, concomitant therapy, and hybrid therapy.
Levofloxacin-based therapy shows impressive efficacy but might be employed as rescue treatment due to rapidly raising resistance.
Rifabutin-based therapy is also regarded as a rescue therapy.
Several factors including antibiotics resistance, patient compliance, and CYP 2C19 genotypes could influence the outcome.
Clinicians should use antibiotics according to local reports.
It is recommended that triple therapy should not be used in areas with high clarithromycin resistance or dual clarithromycin and metronidazole resistance.
American Psychological Association (APA)
Kuo, Chao-Hung& Kuo, Fu-Chen& Hu, Huang-Ming& Liu, Chung-Jung& Wang, Sophie S. W.& Chen, Tun-Chieh…[et al.]. 2012. The Optimal First-Line Therapy of Helicobacter pylori Infection in Year 2012. Gastroenterology Research and Practice،Vol. 2012, no. 2012, pp.1-8.
https://search.emarefa.net/detail/BIM-451312
Modern Language Association (MLA)
Kuo, Chao-Hung…[et al.]. The Optimal First-Line Therapy of Helicobacter pylori Infection in Year 2012. Gastroenterology Research and Practice No. 2012 (2012), pp.1-8.
https://search.emarefa.net/detail/BIM-451312
American Medical Association (AMA)
Kuo, Chao-Hung& Kuo, Fu-Chen& Hu, Huang-Ming& Liu, Chung-Jung& Wang, Sophie S. W.& Chen, Tun-Chieh…[et al.]. The Optimal First-Line Therapy of Helicobacter pylori Infection in Year 2012. Gastroenterology Research and Practice. 2012. Vol. 2012, no. 2012, pp.1-8.
https://search.emarefa.net/detail/BIM-451312
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-451312