Variations in Adipokine Genes AdipoQ, Lep, and LepR Are Associated with Risk for Obesity-Related Metabolic Disease : The Modulatory Role of Gene-Nutrient Interactions
Joint Authors
Taylor, Carla G.
Enns, Jennifer Emily
Zahradka, Peter
Source
Issue
Vol. 2011, Issue 2011 (31 Dec. 2011), pp.1-17, 17 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2011-05-18
Country of Publication
Egypt
No. of Pages
17
Main Subjects
Abstract EN
Obesity rates are rapidly increasing worldwide and facilitate the development of many related disease states, such as cardiovascular disease, the metabolic syndrome, type 2 diabetes mellitus, and various types of cancer.
Variation in metabolically important genes can have a great impact on a population's susceptibility to becoming obese and/or developing related complications.
The adipokines adiponectin and leptin, as well as the leptin receptor, are major players in the regulation of body energy homeostasis and fat storage.
This paper summarizes the findings of single nucleotide polymorphisms in these three genes and their effect on obesity and metabolic disease risk.
Additionally, studies of gene-nutrient interactions involving adiponectin, leptin, and the leptin receptor are highlighted to emphasize the critical role of diet in susceptible populations.
American Psychological Association (APA)
Enns, Jennifer Emily& Taylor, Carla G.& Zahradka, Peter. 2011. Variations in Adipokine Genes AdipoQ, Lep, and LepR Are Associated with Risk for Obesity-Related Metabolic Disease : The Modulatory Role of Gene-Nutrient Interactions. Journal of Obesity،Vol. 2011, no. 2011, pp.1-17.
https://search.emarefa.net/detail/BIM-451340
Modern Language Association (MLA)
Enns, Jennifer Emily…[et al.]. Variations in Adipokine Genes AdipoQ, Lep, and LepR Are Associated with Risk for Obesity-Related Metabolic Disease : The Modulatory Role of Gene-Nutrient Interactions. Journal of Obesity No. 2011 (2011), pp.1-17.
https://search.emarefa.net/detail/BIM-451340
American Medical Association (AMA)
Enns, Jennifer Emily& Taylor, Carla G.& Zahradka, Peter. Variations in Adipokine Genes AdipoQ, Lep, and LepR Are Associated with Risk for Obesity-Related Metabolic Disease : The Modulatory Role of Gene-Nutrient Interactions. Journal of Obesity. 2011. Vol. 2011, no. 2011, pp.1-17.
https://search.emarefa.net/detail/BIM-451340
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-451340