Aluminum Silicate Nanotube Modification of Cotton-Like Siloxane-poly(L-lactic acid)‎-vaterite Composites

Abstract EN

In our earlier work, a cotton-like biodegradable composite, consisting of poly(L-lactic acid) with siloxane-containing vaterite, has been prepared by electrospinning.

In the present work, the fibers skeleton of the cotton-like composites was modified successfully with imogolite, which is hydrophilic and biocompatible, via a dip process using ethanol diluted solution to improve the cellular initial attachment.

Almost no change in the fiber morphology after the surface modification was observed.

The surface-modified composite showed the similar calcium and silicate ions releasabilities, for activating the osteoblasts, as an unmodified one.

Cell culture tests showed that the initial adhesion of murine osteoblast-like cells on the surface of the fibers was enhanced by surface modification.