Attenuation of Hemodynamic Responses to Laryngoscopy and Tracheal Intubation : Propacetamol versus Lidocaine—A Randomized Clinical Trial
Joint Authors
Nabavian, Omid
Vafainejad, Hossein
Reza Feili, Ali
Golbinimofrad, Poorya
Kord Valeshabad, Ali
Rezaei, Mehdi
Koohkan, Mohammad
Darabi, Hamed
Nourijelyani, Keramat
Kord Valeshabad, Reza
Kord, Hadi
Jafari, Samira
Source
Anesthesiology Research and Practice
Issue
Vol. 2014, Issue 2014 (31 Dec. 2014), pp.1-6, 6 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2014-04-13
Country of Publication
Egypt
No. of Pages
6
Main Subjects
Abstract EN
The purpose of this study is to assess the effects of propacetamol on attenuating hemodynamic responses subsequent laryngoscopy and tracheal intubation compared to lidocaine.
In this randomized clinical trial, 62 patients with the American Anesthesiologists Society (ASA) class I/II who required laryngoscopy and tracheal intubation for elective surgery were assigned to receive propacetamol 2 g/I.V./infusion (group P) or lidocaine 1.5 mg/kg (group L) prior to laryngoscopy.
Systolic and diastolic blood pressures (SBP, DBP), mean arterial pressure (MAP), and heart rate (HR) were recorded at baseline, before laryngoscopy and within nine minutes after intubation.
In both groups P and L, MAP increased after laryngoscopy and the changes were statistically significant (P<0.001).
There were significant changes of HR in both groups after intubation (P<0.02), but the trend of changes was different between two groups (P<0.001).
In group L, HR increased after intubation and its change was statistically significant within 9 minutes after intubation (P<0.001), while in group P, HR remained stable after intubation (P=0.8).
Propacetamol 2 gr one hour prior intubation attenuates heart rate responses after laryngoscopy but is not effective to prevent acute alterations in blood pressure after intubation.
American Psychological Association (APA)
Kord Valeshabad, Ali& Nabavian, Omid& Nourijelyani, Keramat& Kord, Hadi& Vafainejad, Hossein& Kord Valeshabad, Reza…[et al.]. 2014. Attenuation of Hemodynamic Responses to Laryngoscopy and Tracheal Intubation : Propacetamol versus Lidocaine—A Randomized Clinical Trial. Anesthesiology Research and Practice،Vol. 2014, no. 2014, pp.1-6.
https://search.emarefa.net/detail/BIM-451465
Modern Language Association (MLA)
Kord Valeshabad, Ali…[et al.]. Attenuation of Hemodynamic Responses to Laryngoscopy and Tracheal Intubation : Propacetamol versus Lidocaine—A Randomized Clinical Trial. Anesthesiology Research and Practice No. 2014 (2014), pp.1-6.
https://search.emarefa.net/detail/BIM-451465
American Medical Association (AMA)
Kord Valeshabad, Ali& Nabavian, Omid& Nourijelyani, Keramat& Kord, Hadi& Vafainejad, Hossein& Kord Valeshabad, Reza…[et al.]. Attenuation of Hemodynamic Responses to Laryngoscopy and Tracheal Intubation : Propacetamol versus Lidocaine—A Randomized Clinical Trial. Anesthesiology Research and Practice. 2014. Vol. 2014, no. 2014, pp.1-6.
https://search.emarefa.net/detail/BIM-451465
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-451465