Tanycytic Ependymoma : A Challenging Histological Diagnosis
Joint Authors
Krisht, Khaled M.
Schmidt, Meic H.
Source
Case Reports in Neurological Medicine
Issue
Vol. 2013, Issue 2013 (31 Dec. 2013), pp.1-5, 5 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2013-02-14
Country of Publication
Egypt
No. of Pages
5
Main Subjects
Abstract EN
Tanycytic ependymoma is a rare form of ependymoma that usually arises in the intramedullary spine.
It has a unique histology emphasized by the inconspicuous ependymal pattern of cells and close resemblance to schwannoma and astrocytoma.
The authors report a 50-year-old man with a cervical tanycytic ependymoma that was initially thought to be a schwannoma.
The frozen histology section showed spindle cells with oval and elongated nuclei with occasional hemosiderin deposits present suggesting a preliminary diagnosis of schwannoma.
Immunohistochemical staining of the permanent section revealed strong immunoreactivity for glial fibrillary acidic protein with intermittent S-100 positivity, confirming that the tumor was a tanycytic ependymoma.
This underlines the challenges involved in making an accurate diagnosis and demonstrates that careful and detailed histological inspection with immunohistochemical stains and ultrastructural microscopy may be necessary to distinguish tanycytic ependymoma from other neoplasms.
American Psychological Association (APA)
Krisht, Khaled M.& Schmidt, Meic H.. 2013. Tanycytic Ependymoma : A Challenging Histological Diagnosis. Case Reports in Neurological Medicine،Vol. 2013, no. 2013, pp.1-5.
https://search.emarefa.net/detail/BIM-451523
Modern Language Association (MLA)
Krisht, Khaled M.& Schmidt, Meic H.. Tanycytic Ependymoma : A Challenging Histological Diagnosis. Case Reports in Neurological Medicine No. 2013 (2013), pp.1-5.
https://search.emarefa.net/detail/BIM-451523
American Medical Association (AMA)
Krisht, Khaled M.& Schmidt, Meic H.. Tanycytic Ependymoma : A Challenging Histological Diagnosis. Case Reports in Neurological Medicine. 2013. Vol. 2013, no. 2013, pp.1-5.
https://search.emarefa.net/detail/BIM-451523
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-451523