Alteration of Interictal Brain Activity in Patients with Temporal Lobe Epilepsy in the Left Dominant Hemisphere : A Resting-State MEG Study
Joint Authors
Zhu, Haitao
Wu, Ting
Zou, Yuanjie
Zhu, Jinlong
Zheng, Gang
Yang, Lu
Zhao, Tiezhu
Wu, Yong
Liu, Hongyi
Zhang, Rui
Source
Issue
Vol. 2014, Issue 2014 (31 Dec. 2014), pp.1-8, 8 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2014-07-20
Country of Publication
Egypt
No. of Pages
8
Main Subjects
Abstract EN
Resting MEG activities were compared between patients with left temporal lobe epilepsy (LTLE) and normal controls.
Using SAMg2, the activities of MEG data were reconstructed and normalized.
Significantly elevated SAMg2 signals were found in LTLE patients in the left temporal lobe and medial structures.
Marked decreases of SAMg2 signals were found in the wide extratemporal lobe regions, such as the bilateral visual cortex.
The study also demonstrated a positive correlation between the seizure frequency and brain activities of the abnormal regions after the multiple linear regression analysis.
These results suggested that the aberrant brain activities not only were related to the epileptogenic zones, but also existed in other extratemporal regions in patients with LTLE.
The activities of the aberrant regions could be further damaged with the increase of the seizure frequency.
Our findings indicated that LTLE could be a multifocal disease, including complex epileptic networks and brain dysfunction networks.
American Psychological Association (APA)
Zhu, Haitao& Zhu, Jinlong& Zhao, Tiezhu& Wu, Yong& Liu, Hongyi& Wu, Ting…[et al.]. 2014. Alteration of Interictal Brain Activity in Patients with Temporal Lobe Epilepsy in the Left Dominant Hemisphere : A Resting-State MEG Study. BioMed Research International،Vol. 2014, no. 2014, pp.1-8.
https://search.emarefa.net/detail/BIM-451576
Modern Language Association (MLA)
Zhu, Haitao…[et al.]. Alteration of Interictal Brain Activity in Patients with Temporal Lobe Epilepsy in the Left Dominant Hemisphere : A Resting-State MEG Study. BioMed Research International No. 2014 (2014), pp.1-8.
https://search.emarefa.net/detail/BIM-451576
American Medical Association (AMA)
Zhu, Haitao& Zhu, Jinlong& Zhao, Tiezhu& Wu, Yong& Liu, Hongyi& Wu, Ting…[et al.]. Alteration of Interictal Brain Activity in Patients with Temporal Lobe Epilepsy in the Left Dominant Hemisphere : A Resting-State MEG Study. BioMed Research International. 2014. Vol. 2014, no. 2014, pp.1-8.
https://search.emarefa.net/detail/BIM-451576
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-451576