Human Genetics of Diabetic Retinopathy : Current Perspectives
Author
Source
Issue
Vol. 2010, Issue 2010 (31 Dec. 2010), pp.1-6, 6 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2010-07-13
Country of Publication
Egypt
No. of Pages
6
Main Subjects
Abstract EN
Diabetic retinopathy (DR) is a most severe microvascular complication which, if left unchecked, can be sight-threatening.
With the global prevalence of diabetes being relentlessly projected to rise to 438 million subjects by 2030, DR will undoubtedly pose a major public health concern.
Efforts to unravel the human genetics of DR have been undertaken using the candidate gene and linkage approaches, while GWAS efforts are still lacking.
Aside from evidence for a few genes including aldose reductase and vascular endothelial growth factor, the genetics of DR remain poorly elucidated.
Nevertheless, the promise of impactful scientific discoveries may be realized if concerted and collaborative efforts are mounted to identify the genes for DR.
Harnessing new genetic technologies and resources such as the upcoming 1000 Genomes Project will help advance this field of research, and potentially lead to a rich harvest of insights into the biological mechanisms underlying this debilitating complication.
American Psychological Association (APA)
Ng, Daniel P. K.. 2010. Human Genetics of Diabetic Retinopathy : Current Perspectives. Journal of Ophthalmology،Vol. 2010, no. 2010, pp.1-6.
https://search.emarefa.net/detail/BIM-451667
Modern Language Association (MLA)
Ng, Daniel P. K.. Human Genetics of Diabetic Retinopathy : Current Perspectives. Journal of Ophthalmology No. 2010 (2010), pp.1-6.
https://search.emarefa.net/detail/BIM-451667
American Medical Association (AMA)
Ng, Daniel P. K.. Human Genetics of Diabetic Retinopathy : Current Perspectives. Journal of Ophthalmology. 2010. Vol. 2010, no. 2010, pp.1-6.
https://search.emarefa.net/detail/BIM-451667
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-451667