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Intermuscular Adipose Tissue Is Muscle Specific and Associated with Poor Functional Performance
Joint Authors
Sinacore, David R.
Tuttle, Lori J.
Mueller, Michael J.
Source
Issue
Vol. 2012, Issue 2012 (31 Dec. 2012), pp.1-7, 7 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2012-05-14
Country of Publication
Egypt
No. of Pages
7
Main Subjects
Pharmacy, Health & Medical Sciences
Abstract EN
Purpose.
People with obesity, diabetes, and peripheral neuropathy have high levels of intermuscular adipose tissue (IMAT) volume which has been inversely related to physical function.
We determined if IMAT is muscle specific, if calf IMAT is different between a healthy obese group (HO), a group with diabetes mellitus (D), and a group with diabetes mellitus and peripheral neuropathy (DN), and if IMAT volume or the ratio of IMAT/muscle volume is related to physical function in these groups.
Methods.
10 healthy obese people, 11 with type 2 diabetes, 24 with diabetes and peripheral neuropathy, had assessments of muscle morphology, physical function and muscle performance.
Results.
The gastrocnemius muscle had a higher ratio of IMAT/muscle volume than any other muscle or compartment.
There were no differences between groups in calf muscle or IMAT volumes.
Calf IMAT was inversely related to physical performance on the 6-minute walk test (r=−0.47) and physical performance test (r=−0.36).
IMAT/muscle volume was inversely related to physical performance (PPT, r=−0.44; 6 MW r=−0.48; stair power, r=−0.30).
Conclusions.
IMAT accumulation varies in calf muscles, is highest in the gastrocnemius muscle, and is associated with poor physical performance.
American Psychological Association (APA)
Tuttle, Lori J.& Sinacore, David R.& Mueller, Michael J.. 2012. Intermuscular Adipose Tissue Is Muscle Specific and Associated with Poor Functional Performance. Journal of Aging Research،Vol. 2012, no. 2012, pp.1-7.
https://search.emarefa.net/detail/BIM-451703
Modern Language Association (MLA)
Tuttle, Lori J.…[et al.]. Intermuscular Adipose Tissue Is Muscle Specific and Associated with Poor Functional Performance. Journal of Aging Research No. 2012 (2012), pp.1-7.
https://search.emarefa.net/detail/BIM-451703
American Medical Association (AMA)
Tuttle, Lori J.& Sinacore, David R.& Mueller, Michael J.. Intermuscular Adipose Tissue Is Muscle Specific and Associated with Poor Functional Performance. Journal of Aging Research. 2012. Vol. 2012, no. 2012, pp.1-7.
https://search.emarefa.net/detail/BIM-451703
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-451703