Ileocecal Adenocarcinoma and Ureteral Transitional Cell Carcinoma with Multiple Sebaceous Tumors and Keratoacanthomas in a Case of Muir-Torre Syndrome
Joint Authors
Lynch, Michael C.
Anderson, Bryan E.
Source
Dermatology Research and Practice
Issue
Vol. 2010, Issue 2010 (31 Dec. 2010), pp.1-3, 3 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2010-08-15
Country of Publication
Egypt
No. of Pages
3
Main Subjects
Abstract EN
Cutaneous neoplasms including sebaceous tumors, keratoacanthomas, and basal cell carcinomas with sebaceous differentiation can be markers of internal malignancy associated with the Muir-Torre Syndrome (MTS).
We report a 56-year-old man with a diagnosis of hereditary nonpolyposis colorectal cancer (HNPCC) and ureteral transitional cell carcinoma who subsequently developed two sebaceous gland neoplasms and several keratoacanthomas, leading to the diagnosis of MTS.
Our case highlights the clinical advantages of immunohistochemistry (IHC) in identifying mutations in the mismatch repair (MMR) genes responsible for both HNPCC and MTS.
The importance of continued clinical suspicion in the dermatological assessment of patients with sebaceous neoplasms is emphasized.
American Psychological Association (APA)
Lynch, Michael C.& Anderson, Bryan E.. 2010. Ileocecal Adenocarcinoma and Ureteral Transitional Cell Carcinoma with Multiple Sebaceous Tumors and Keratoacanthomas in a Case of Muir-Torre Syndrome. Dermatology Research and Practice،Vol. 2010, no. 2010, pp.1-3.
https://search.emarefa.net/detail/BIM-451721
Modern Language Association (MLA)
Lynch, Michael C.& Anderson, Bryan E.. Ileocecal Adenocarcinoma and Ureteral Transitional Cell Carcinoma with Multiple Sebaceous Tumors and Keratoacanthomas in a Case of Muir-Torre Syndrome. Dermatology Research and Practice No. 2010 (2010), pp.1-3.
https://search.emarefa.net/detail/BIM-451721
American Medical Association (AMA)
Lynch, Michael C.& Anderson, Bryan E.. Ileocecal Adenocarcinoma and Ureteral Transitional Cell Carcinoma with Multiple Sebaceous Tumors and Keratoacanthomas in a Case of Muir-Torre Syndrome. Dermatology Research and Practice. 2010. Vol. 2010, no. 2010, pp.1-3.
https://search.emarefa.net/detail/BIM-451721
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-451721