Relationship between Serum Lipoprotein Ratios and Insulin Resistance in Polycystic Ovary Syndrome
Joint Authors
Zhuang, Qi
Xiang, Shou-Kui
Qian, Feng-Juan
Hua, Fei
Jiang, Xiao-Hong
Tang, Ying
Source
International Journal of Endocrinology
Issue
Vol. 2012, Issue 2012 (31 Dec. 2012), pp.1-4, 4 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2012-06-25
Country of Publication
Egypt
No. of Pages
4
Main Subjects
Abstract EN
Objective.
To investigate the association between serum lipoprotein ratios and insulin resistance in women with polycystic ovarian syndrome (PCOS).
Methods.
105 PCOS patients and 109 controls were randomly enrolled in the study.
Serum levels of luteinizing hormone (LH), follicle-stimulating hormone (FSH), estradiol (E2), total testosterone (T), fasting glucose (FBG), fasting insulin (FINS), serum triglycerides (TG), total cholesterol (TC), high-density lipoprotein (HDL-C), and low-density lipoprotein (LDL-C) levels were checked, and then TG/HDL-C ratio, TC/HDL-C, ratio and LDL-C/HDL-C ratio were calculated.
The homeostasis model assessment of insulin resistance (HOMA-IR) was used to calculate the insulin resistance.
Results.
All lipoprotein ratios were significantly higher in PCOS patients as compared to healthy controls (P<0.05).
TG/HDL-C ratio, TC/HDL-C ratio, and LDL-C/HDL-C ratio were significantly correlated with HOMA-IR (P<0.05).
The ROC curve demonstrated that TC/HDL-C ratio had higher sensitivity and specificity in diagnosing PCOS with insulin resistance.
Conclusion.
This study demonstrates that serum lipoprotein ratio significantly correlates with insulin resistance and can be used as the marker of insulin resistance in PCOS patients.
American Psychological Association (APA)
Xiang, Shou-Kui& Hua, Fei& Tang, Ying& Jiang, Xiao-Hong& Zhuang, Qi& Qian, Feng-Juan. 2012. Relationship between Serum Lipoprotein Ratios and Insulin Resistance in Polycystic Ovary Syndrome. International Journal of Endocrinology،Vol. 2012, no. 2012, pp.1-4.
https://search.emarefa.net/detail/BIM-451736
Modern Language Association (MLA)
Xiang, Shou-Kui…[et al.]. Relationship between Serum Lipoprotein Ratios and Insulin Resistance in Polycystic Ovary Syndrome. International Journal of Endocrinology No. 2012 (2012), pp.1-4.
https://search.emarefa.net/detail/BIM-451736
American Medical Association (AMA)
Xiang, Shou-Kui& Hua, Fei& Tang, Ying& Jiang, Xiao-Hong& Zhuang, Qi& Qian, Feng-Juan. Relationship between Serum Lipoprotein Ratios and Insulin Resistance in Polycystic Ovary Syndrome. International Journal of Endocrinology. 2012. Vol. 2012, no. 2012, pp.1-4.
https://search.emarefa.net/detail/BIM-451736
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-451736