MicroRNA in Diabetic Nephropathy : Renin Angiotensin, AGERAGE, and Oxidative Stress Pathway
Joint Authors
McClelland, Aaron
Kantharidis, Phillip
Hagiwara, Shinji
Source
Issue
Vol. 2013, Issue 2013 (31 Dec. 2013), pp.1-11, 11 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2013-12-15
Country of Publication
Egypt
No. of Pages
11
Main Subjects
Abstract EN
MicroRNAs (miRNA) are a novel class of small, noncoding RNA molecules that have gained the attention of many researchers in recent years due to their ability to posttranscriptionally regulate the expression of families of genes simultaneously.
Their role in normal physiology and pathobiology is intriguing and their regulation in normal and disease states is fascinating.
That the cells can return to a state of homeostasis when these small molecules are perturbed is truly remarkable given the multiple cellular targets of each miRNA and that many mRNAs are targeted by multiple miRNAs.
Several reviews have covered aspects of miRNA function in biology and disease.
Here, we review the role of miRNA in regulating the renin-angiotensin system, AGE/RAGE signalling, and under conditions of oxidative stress in the context of diabetic nephropathy.
American Psychological Association (APA)
Hagiwara, Shinji& McClelland, Aaron& Kantharidis, Phillip. 2013. MicroRNA in Diabetic Nephropathy : Renin Angiotensin, AGERAGE, and Oxidative Stress Pathway. Journal of Diabetes Research،Vol. 2013, no. 2013, pp.1-11.
https://search.emarefa.net/detail/BIM-451783
Modern Language Association (MLA)
Hagiwara, Shinji…[et al.]. MicroRNA in Diabetic Nephropathy : Renin Angiotensin, AGERAGE, and Oxidative Stress Pathway. Journal of Diabetes Research No. 2013 (2013), pp.1-11.
https://search.emarefa.net/detail/BIM-451783
American Medical Association (AMA)
Hagiwara, Shinji& McClelland, Aaron& Kantharidis, Phillip. MicroRNA in Diabetic Nephropathy : Renin Angiotensin, AGERAGE, and Oxidative Stress Pathway. Journal of Diabetes Research. 2013. Vol. 2013, no. 2013, pp.1-11.
https://search.emarefa.net/detail/BIM-451783
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-451783