Emergent Central Pattern Generator Behavior in Gap-Junction-Coupled Hodgkin-Huxley Style Neuron Model
Joint Authors
Solomon, Irene C.
Memelli, Heraldo
Horn, Kyle G.
Source
Computational Intelligence and Neuroscience
Issue
Vol. 2012, Issue 2012 (31 Dec. 2012), pp.1-10, 10 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2012-12-06
Country of Publication
Egypt
No. of Pages
10
Main Subjects
Abstract EN
Most models of central pattern generators (CPGs) involve two distinct nuclei mutually inhibiting one another via synapses.
Here, we present a single-nucleus model of biologically realistic Hodgkin-Huxley neurons with random gap junction coupling.
Despite no explicit division of neurons into two groups, we observe a spontaneous division of neurons into two distinct firing groups.
In addition, we also demonstrate this phenomenon in a simplified version of the model, highlighting the importance of afterhyperpolarization currents (IAHP) to CPGs utilizing gap junction coupling.
The properties of these CPGs also appear sensitive to gap junction conductance, probability of gap junction coupling between cells, topology of gap junction coupling, and, to a lesser extent, input current into our simulated nucleus.
American Psychological Association (APA)
Horn, Kyle G.& Memelli, Heraldo& Solomon, Irene C.. 2012. Emergent Central Pattern Generator Behavior in Gap-Junction-Coupled Hodgkin-Huxley Style Neuron Model. Computational Intelligence and Neuroscience،Vol. 2012, no. 2012, pp.1-10.
https://search.emarefa.net/detail/BIM-451800
Modern Language Association (MLA)
Horn, Kyle G.…[et al.]. Emergent Central Pattern Generator Behavior in Gap-Junction-Coupled Hodgkin-Huxley Style Neuron Model. Computational Intelligence and Neuroscience No. 2012 (2012), pp.1-10.
https://search.emarefa.net/detail/BIM-451800
American Medical Association (AMA)
Horn, Kyle G.& Memelli, Heraldo& Solomon, Irene C.. Emergent Central Pattern Generator Behavior in Gap-Junction-Coupled Hodgkin-Huxley Style Neuron Model. Computational Intelligence and Neuroscience. 2012. Vol. 2012, no. 2012, pp.1-10.
https://search.emarefa.net/detail/BIM-451800
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-451800