Role of FNA and Core Biopsy of Primary and Metastatic Liver Disease

Joint Authors

Bishop, John
Corwin, Michael T.
Howell, Lydia
Lamba, Ramit
Webb, John
McGahan, John P.
Torok, Natalie

Source

International Journal of Hepatology

Issue

Vol. 2013, Issue 2013 (31 Dec. 2013), pp.1-10, 10 p.

Publisher

Hindawi Publishing Corporation

Publication Date

2013-11-21

Country of Publication

Egypt

No. of Pages

10

Main Subjects

Medicine

Abstract EN

Objective.

To examine our experience with cytology and histology biopsy of the liver and to define methods for improvement of diagnosis of primary liver tumors.

Methods.

This include retrospective study of 189 biopsies of 185 liver masses for cytological or histological analysis.

Patients were subdivided into two groups.

Group 1 consisted of 124 suspected metastasis.

Group 2 consisted of 61 suspected primary neoplasms.

Biopsies were considered positive or equivocal.

In equivocal cases, special stains were performed.

In Group 2, cases were classified by contrast CT or MRI as to (I) classic HCC, (II) infiltrated HCC, or (Ill) equivocal.

Results.

Definitive diagnosis was obtained in 117/124 masses (94%) in Group 1, 48/61 masses (79%) in Group 2, and (Ill) equivocal 13 cases in Group II.

In two equivocal cases in which special stains were performed, they were reclassified as HCC.

In 8/13 cases, CT findings were consistent with HCC.

Conclusion.

Liver biopsies are useful in obtaining a definitive diagnosis of suspected metastatic liver disease.

Biopsy results are less reliable in patients with suspected primary liver tumors.

In these situations, strategies can include basing treatment on imaging criteria or use of newer special pathological stains.

Advances in Knowledge.

Use of newer special immunological stains improves accuracy in definitive diagnosis of primary liver tumors.

American Psychological Association (APA)

McGahan, John P.& Bishop, John& Webb, John& Howell, Lydia& Torok, Natalie& Lamba, Ramit…[et al.]. 2013. Role of FNA and Core Biopsy of Primary and Metastatic Liver Disease. International Journal of Hepatology،Vol. 2013, no. 2013, pp.1-10.
https://search.emarefa.net/detail/BIM-451818

Modern Language Association (MLA)

McGahan, John P.…[et al.]. Role of FNA and Core Biopsy of Primary and Metastatic Liver Disease. International Journal of Hepatology No. 2013 (2013), pp.1-10.
https://search.emarefa.net/detail/BIM-451818

American Medical Association (AMA)

McGahan, John P.& Bishop, John& Webb, John& Howell, Lydia& Torok, Natalie& Lamba, Ramit…[et al.]. Role of FNA and Core Biopsy of Primary and Metastatic Liver Disease. International Journal of Hepatology. 2013. Vol. 2013, no. 2013, pp.1-10.
https://search.emarefa.net/detail/BIM-451818

Data Type

Journal Articles

Language

English

Notes

Includes bibliographical references

Record ID

BIM-451818