Role of FNA and Core Biopsy of Primary and Metastatic Liver Disease
Joint Authors
Bishop, John
Corwin, Michael T.
Howell, Lydia
Lamba, Ramit
Webb, John
McGahan, John P.
Torok, Natalie
Source
International Journal of Hepatology
Issue
Vol. 2013, Issue 2013 (31 Dec. 2013), pp.1-10, 10 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2013-11-21
Country of Publication
Egypt
No. of Pages
10
Main Subjects
Abstract EN
Objective.
To examine our experience with cytology and histology biopsy of the liver and to define methods for improvement of diagnosis of primary liver tumors.
Methods.
This include retrospective study of 189 biopsies of 185 liver masses for cytological or histological analysis.
Patients were subdivided into two groups.
Group 1 consisted of 124 suspected metastasis.
Group 2 consisted of 61 suspected primary neoplasms.
Biopsies were considered positive or equivocal.
In equivocal cases, special stains were performed.
In Group 2, cases were classified by contrast CT or MRI as to (I) classic HCC, (II) infiltrated HCC, or (Ill) equivocal.
Results.
Definitive diagnosis was obtained in 117/124 masses (94%) in Group 1, 48/61 masses (79%) in Group 2, and (Ill) equivocal 13 cases in Group II.
In two equivocal cases in which special stains were performed, they were reclassified as HCC.
In 8/13 cases, CT findings were consistent with HCC.
Conclusion.
Liver biopsies are useful in obtaining a definitive diagnosis of suspected metastatic liver disease.
Biopsy results are less reliable in patients with suspected primary liver tumors.
In these situations, strategies can include basing treatment on imaging criteria or use of newer special pathological stains.
Advances in Knowledge.
Use of newer special immunological stains improves accuracy in definitive diagnosis of primary liver tumors.
American Psychological Association (APA)
McGahan, John P.& Bishop, John& Webb, John& Howell, Lydia& Torok, Natalie& Lamba, Ramit…[et al.]. 2013. Role of FNA and Core Biopsy of Primary and Metastatic Liver Disease. International Journal of Hepatology،Vol. 2013, no. 2013, pp.1-10.
https://search.emarefa.net/detail/BIM-451818
Modern Language Association (MLA)
McGahan, John P.…[et al.]. Role of FNA and Core Biopsy of Primary and Metastatic Liver Disease. International Journal of Hepatology No. 2013 (2013), pp.1-10.
https://search.emarefa.net/detail/BIM-451818
American Medical Association (AMA)
McGahan, John P.& Bishop, John& Webb, John& Howell, Lydia& Torok, Natalie& Lamba, Ramit…[et al.]. Role of FNA and Core Biopsy of Primary and Metastatic Liver Disease. International Journal of Hepatology. 2013. Vol. 2013, no. 2013, pp.1-10.
https://search.emarefa.net/detail/BIM-451818
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-451818