Immune Microenvironment in Colorectal Cancer : A New Hallmark to Change Old Paradigms
Joint Authors
Vicente Baz, David
de la Cruz-Merino, Luis
Pulido, Enrique Grande
Codes Manuel de Villena, Manuel
Henao Carrasco, Fernando
Reina Zoilo, Juan José
Nogales Fernández, Esteban
Source
Clinical and Developmental Immunology
Issue
Vol. 2011, Issue 2011 (31 Dec. 2011), pp.1-9, 9 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2011-11-24
Country of Publication
Egypt
No. of Pages
9
Main Subjects
Abstract EN
Impact of immune microenvironment in prognosis of solid tumors has been extensively studied in the last few years.
Specifically in colorectal carcinoma, increased knowledge of the immune events around these tumors and their relation with clinical outcomes have led to consider immune microenvironment as one of the most important prognostic factors in this disease.
In this review we will summarize and update the current knowledge with respect to this intriguing and complex new hallmark of cancer, paying special attention to infiltration by T-infiltrating lymphocytes and their subtypes in colorectal cancer, as well as its eventual clinical translation in terms of long-term prognosis.
Finally, we suggest some possible investigational approaches based on combinatorial strategies to trigger and boost immune reaction against tumor cells.
American Psychological Association (APA)
de la Cruz-Merino, Luis& Henao Carrasco, Fernando& Vicente Baz, David& Nogales Fernández, Esteban& Reina Zoilo, Juan José& Codes Manuel de Villena, Manuel…[et al.]. 2011. Immune Microenvironment in Colorectal Cancer : A New Hallmark to Change Old Paradigms. Clinical and Developmental Immunology،Vol. 2011, no. 2011, pp.1-9.
https://search.emarefa.net/detail/BIM-451823
Modern Language Association (MLA)
de la Cruz-Merino, Luis…[et al.]. Immune Microenvironment in Colorectal Cancer : A New Hallmark to Change Old Paradigms. Clinical and Developmental Immunology No. 2011 (2011), pp.1-9.
https://search.emarefa.net/detail/BIM-451823
American Medical Association (AMA)
de la Cruz-Merino, Luis& Henao Carrasco, Fernando& Vicente Baz, David& Nogales Fernández, Esteban& Reina Zoilo, Juan José& Codes Manuel de Villena, Manuel…[et al.]. Immune Microenvironment in Colorectal Cancer : A New Hallmark to Change Old Paradigms. Clinical and Developmental Immunology. 2011. Vol. 2011, no. 2011, pp.1-9.
https://search.emarefa.net/detail/BIM-451823
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-451823