Assessment of Endothelial Dysfunction in Childhood Obesity and Clinical Use
Joint Authors
Bruyndonckx, Luc
Vrints, Christiaan J.
Vissers, Dirk K.
Hoymans, Vicky Y.
Conraads, Viviane M.
Ramet, José
Van Craenenbroeck, Amaryllis H.
Source
Oxidative Medicine and Cellular Longevity
Issue
Vol. 2013, Issue 2013 (31 Dec. 2013), pp.1-19, 19 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2013-04-03
Country of Publication
Egypt
No. of Pages
19
Main Subjects
Natural & Life Sciences (Multidisciplinary)
Biology
Abstract EN
The association of obesity with noncommunicable diseases, such as cardiovascular complications and diabetes, is considered a major threat to the management of health care worldwide.
Epidemiological findings show that childhood obesity is rapidly rising in Western society, as well as in developing countries.
This pandemic is not without consequences and can affect the risk of future cardiovascular disease in these children.
Childhood obesity is associated with endothelial dysfunction, the first yet still reversible step towards atherosclerosis.
Advanced research techniques have added further insight on how childhood obesity and associated comorbidities lead to endothelial dysfunction.
Techniques used to measure endothelial function were further brought to perfection, and novel biomarkers, including endothelial progenitor cells, were discovered.
The aim of this paper is to provide a critical overview on both in vivo as well as in vitro markers for endothelial integrity.
Additionally, an in-depth description of the mechanisms that disrupt the delicate balance between endothelial damage and repair will be given.
Finally, the effects of lifestyle interventions and pharmacotherapy on endothelial dysfunction will be reviewed.
American Psychological Association (APA)
Bruyndonckx, Luc& Hoymans, Vicky Y.& Van Craenenbroeck, Amaryllis H.& Vissers, Dirk K.& Vrints, Christiaan J.& Ramet, José…[et al.]. 2013. Assessment of Endothelial Dysfunction in Childhood Obesity and Clinical Use. Oxidative Medicine and Cellular Longevity،Vol. 2013, no. 2013, pp.1-19.
https://search.emarefa.net/detail/BIM-451872
Modern Language Association (MLA)
Bruyndonckx, Luc…[et al.]. Assessment of Endothelial Dysfunction in Childhood Obesity and Clinical Use. Oxidative Medicine and Cellular Longevity No. 2013 (2013), pp.1-19.
https://search.emarefa.net/detail/BIM-451872
American Medical Association (AMA)
Bruyndonckx, Luc& Hoymans, Vicky Y.& Van Craenenbroeck, Amaryllis H.& Vissers, Dirk K.& Vrints, Christiaan J.& Ramet, José…[et al.]. Assessment of Endothelial Dysfunction in Childhood Obesity and Clinical Use. Oxidative Medicine and Cellular Longevity. 2013. Vol. 2013, no. 2013, pp.1-19.
https://search.emarefa.net/detail/BIM-451872
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-451872