Pathological Complete Response of Advanced Rectal Cancer Treated by Preoperative Chemoradiotherapy with Oral Tegafur-Uracil and Leucovorin : A Case Report
Joint Authors
Masuzawa, Toru
Tori, Masayuki
Wakasugi, Masaki
Tei, Mitsuyoshi
Ueshima, Shigeyuki
Tsujimoto, Masahiko
Omori, Takeshi
Akamatsu, Hiroki
Source
Case Reports in Oncological Medicine
Issue
Vol. 2013, Issue 2013 (31 Dec. 2013), pp.1-3, 3 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2013-11-30
Country of Publication
Egypt
No. of Pages
3
Main Subjects
Abstract EN
A rare case of pathological complete response of advanced rectal cancer treated by preoperative chemoradiotherapy (CRT) with oral tegafur-uracil and leucovorin is reported.
A 73-year-old man with bloody stool was diagnosed with type 2 rectal cancer located 6 cm from the anal verge.
Examination of biopsy specimens revealed moderately differentiated adenocarcinoma.
Computed tomography scans showed no distant or lymph node metastases.
With a diagnosis of advanced lower rectal cancer of T3N0M0 stage III according to the TNM classification, he underwent preoperative CRT with oral tegafur-uracil and leucovorin.
He did not experience any adverse events due to CRT.
An abdominal CT scan and colonoscopy after CRT demonstrated significant tumor reduction.
Then, 63 days after CRT, he underwent laparoscopic-assisted low anterior resection and diverting ileostomy.
Pathological examination revealed no residual cancer cells.
During 15 months of follow-up after his ileostomy was taken down, the patient continued to do well without any signs of recurrence or metastasis.
Preoperative CRT with tegafur-uracil and leucovorin may thus represent a safe, well-tolerated, and effective therapeutic strategy for patients with advanced rectal cancer.
American Psychological Association (APA)
Wakasugi, Masaki& Masuzawa, Toru& Tei, Mitsuyoshi& Omori, Takeshi& Ueshima, Shigeyuki& Tori, Masayuki…[et al.]. 2013. Pathological Complete Response of Advanced Rectal Cancer Treated by Preoperative Chemoradiotherapy with Oral Tegafur-Uracil and Leucovorin : A Case Report. Case Reports in Oncological Medicine،Vol. 2013, no. 2013, pp.1-3.
https://search.emarefa.net/detail/BIM-451932
Modern Language Association (MLA)
Wakasugi, Masaki…[et al.]. Pathological Complete Response of Advanced Rectal Cancer Treated by Preoperative Chemoradiotherapy with Oral Tegafur-Uracil and Leucovorin : A Case Report. Case Reports in Oncological Medicine No. 2013 (2013), pp.1-3.
https://search.emarefa.net/detail/BIM-451932
American Medical Association (AMA)
Wakasugi, Masaki& Masuzawa, Toru& Tei, Mitsuyoshi& Omori, Takeshi& Ueshima, Shigeyuki& Tori, Masayuki…[et al.]. Pathological Complete Response of Advanced Rectal Cancer Treated by Preoperative Chemoradiotherapy with Oral Tegafur-Uracil and Leucovorin : A Case Report. Case Reports in Oncological Medicine. 2013. Vol. 2013, no. 2013, pp.1-3.
https://search.emarefa.net/detail/BIM-451932
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-451932