Probiotic Bacteria Influence the Composition and Function of the Intestinal Microbiota
Joint Authors
O'Toole, Paul W.
Cooney, Jakki C.
Source
Interdisciplinary Perspectives on Infectious Diseases
Issue
Vol. 2008, Issue 2008 (31 Dec. 2008), pp.1-9, 9 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2008-12-03
Country of Publication
Egypt
No. of Pages
9
Main Subjects
Abstract EN
Probiotics have a range of proposed health benefits for the consumer, which may include modulating the levels of beneficial elements in the microbiota.
Recent investigations using molecular approaches have revealed a human intestinal microbiota comprising over 1000 phylotypes.
Mechanisms whereby probiotics impact on the intestinal microbiota include competition for substrates, direct antagonism by inhibitory substances, competitive exclusion, and potentially host-mediated effects such as improved barrier function and altered immune response.
We now have the microbial inventories and genetic blueprints to begin tackling intestinal microbial ecology at an unprecedented level of detail, aided by the understanding that dietary components may be utilized differentially by individual phylotypes.
Controlled intervention studies in humans, utilizing latest molecular technologies, are required to consolidate evidence for bacterial species that impact on the microbiota.
Mechanistic insights should be provided by metabolomics and other analytical techniques for small molecules.
Rigorous characterization of interactions between the diet, microbiota, and probiotic bacteria will provide new opportunities for modulating the microbiota towards improving human health.
American Psychological Association (APA)
O'Toole, Paul W.& Cooney, Jakki C.. 2008. Probiotic Bacteria Influence the Composition and Function of the Intestinal Microbiota. Interdisciplinary Perspectives on Infectious Diseases،Vol. 2008, no. 2008, pp.1-9.
https://search.emarefa.net/detail/BIM-451939
Modern Language Association (MLA)
O'Toole, Paul W.& Cooney, Jakki C.. Probiotic Bacteria Influence the Composition and Function of the Intestinal Microbiota. Interdisciplinary Perspectives on Infectious Diseases No. 2008 (2008), pp.1-9.
https://search.emarefa.net/detail/BIM-451939
American Medical Association (AMA)
O'Toole, Paul W.& Cooney, Jakki C.. Probiotic Bacteria Influence the Composition and Function of the Intestinal Microbiota. Interdisciplinary Perspectives on Infectious Diseases. 2008. Vol. 2008, no. 2008, pp.1-9.
https://search.emarefa.net/detail/BIM-451939
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-451939