Lipoprotein(a) Is the Best Single Marker in Assessing Unstable Angina Pectoris
Joint Authors
Popović, Lidija
Stojanović, Ivana
Djordjević, Vidosava B.
Vlahović, Predrag
Kundalić, Slavica
Deljanin-Ilić, Marina
Ćosić, Vladan
Zvezdanović, Lilika
Source
Cardiology Research and Practice
Issue
Vol. 2011, Issue 2011 (31 Dec. 2011), pp.1-13, 13 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2011-03-07
Country of Publication
Egypt
No. of Pages
13
Main Subjects
Abstract EN
This study evaluated whether statin therapy changed a diagnostic validity of lipid and inflammatory markers in ischemic heart disease (IHD) patients.
Levels of lipids, lipoproteins, apolipoproteins, inflammatory markers, and atherogenic indexes were determined in 49 apparently healthy men and women, 82 patients having stable angina pectoris (SAP), 80 patients with unstable angina (USAP), and 106 patients with acute ST-elevation myocardial infarction (STEMI) treated or not treated with statins.
Diagnostic accuracy of markers was determined by ROC curve analysis.
Significantly lower apoA-I in all statin-treated groups and significantly higher apoB in statin-treated STEMI group compared to non-statin-treated groups were observed.
CRP showed the best ROC characteristics in the assessment of STEMI patients.
Lp(a) is better in the evaluation of SAP and USAP patients, considering that Lp(a) showed the highest area under the curve (AUC).
Regarding atherogenic indexes, the highest AUC in SAP group was obtained for TG/apoB and in USAP and STEMI patients for TG/HDL-c.
Statins lowered total cholesterol, LDL-c, and TG but fail to normalize apoA-I in patients with IHD.
American Psychological Association (APA)
Djordjević, Vidosava B.& Ćosić, Vladan& Stojanović, Ivana& Kundalić, Slavica& Zvezdanović, Lilika& Deljanin-Ilić, Marina…[et al.]. 2011. Lipoprotein(a) Is the Best Single Marker in Assessing Unstable Angina Pectoris. Cardiology Research and Practice،Vol. 2011, no. 2011, pp.1-13.
https://search.emarefa.net/detail/BIM-451948
Modern Language Association (MLA)
Djordjević, Vidosava B.…[et al.]. Lipoprotein(a) Is the Best Single Marker in Assessing Unstable Angina Pectoris. Cardiology Research and Practice No. 2011 (2011), pp.1-13.
https://search.emarefa.net/detail/BIM-451948
American Medical Association (AMA)
Djordjević, Vidosava B.& Ćosić, Vladan& Stojanović, Ivana& Kundalić, Slavica& Zvezdanović, Lilika& Deljanin-Ilić, Marina…[et al.]. Lipoprotein(a) Is the Best Single Marker in Assessing Unstable Angina Pectoris. Cardiology Research and Practice. 2011. Vol. 2011, no. 2011, pp.1-13.
https://search.emarefa.net/detail/BIM-451948
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-451948