Primary Graft Failure after Heart Transplantation
Joint Authors
Watson, Alasdair
Doyle, Aoife
Kotlyar, Eugene
Kumarasinghe, Gayathri
Keogh, Anne M.
Gao, Ling
Jansz, Paul
Macdonald, Peter Simon
Iyer, Arjun
Hicks, Mark
Hayward, Christopher
Granger, Emily
Pye, Roger
Spratt, Phillip
Dhital, Kumud
Source
Issue
Vol. 2011, Issue 2011 (31 Dec. 2011), pp.1-9, 9 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2011-08-01
Country of Publication
Egypt
No. of Pages
9
Main Subjects
Abstract EN
Primary graft failure (PGF) is a devastating complication that occurs in the immediate postoperative period following heart transplantation.
It manifests as severe ventricular dysfunction of the donor graft and carries significant mortality and morbidity.
In the last decade, advances in pharmacological treatment and mechanical circulatory support have improved the outlook for heart transplant recipients who develop this complication.
Despite these advances in treatment, PGF is still the leading cause of death in the first 30 days after transplantation.
In today's climate of significant organ shortages and growing waiting lists, transplant units worldwide have increasingly utilised “marginal donors” to try and bridge the gap between “supply and demand.” One of the costs of this strategy has been an increased incidence of PGF.
As the threat of PGF increases, the challenges of predicting and preventing its occurrence, as well as the identification of more effective treatment modalities, are vital areas of active research and development.
American Psychological Association (APA)
Iyer, Arjun& Kumarasinghe, Gayathri& Hicks, Mark& Watson, Alasdair& Gao, Ling& Doyle, Aoife…[et al.]. 2011. Primary Graft Failure after Heart Transplantation. Journal of Transplantation،Vol. 2011, no. 2011, pp.1-9.
https://search.emarefa.net/detail/BIM-451978
Modern Language Association (MLA)
Iyer, Arjun…[et al.]. Primary Graft Failure after Heart Transplantation. Journal of Transplantation No. 2011 (2011), pp.1-9.
https://search.emarefa.net/detail/BIM-451978
American Medical Association (AMA)
Iyer, Arjun& Kumarasinghe, Gayathri& Hicks, Mark& Watson, Alasdair& Gao, Ling& Doyle, Aoife…[et al.]. Primary Graft Failure after Heart Transplantation. Journal of Transplantation. 2011. Vol. 2011, no. 2011, pp.1-9.
https://search.emarefa.net/detail/BIM-451978
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-451978