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Nonnegative Mixed-Norm Convex Optimization for Mitotic Cell Detection in Phase Contrast Microscopy
Joint Authors
Gao, Zan
Su, Yuting
Yang, Zhaoxuan
Liu, Anan
Hao, Tong
Source
Computational and Mathematical Methods in Medicine
Issue
Vol. 2013, Issue 2013 (31 Dec. 2013), pp.1-10, 10 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2013-11-19
Country of Publication
Egypt
No. of Pages
10
Main Subjects
Abstract EN
This paper proposes a nonnegative mix-norm convex optimization method for mitotic cell detection.
First, we apply an imaging model-based microscopy image segmentation method that exploits phase contrast optics to extract mitotic candidates in the input images.
Then, a convex objective function regularized by mix-norm with nonnegative constraint is proposed to induce sparsity and consistence for discriminative representation of deformable objects in a sparse representation scheme.
At last, a Support Vector Machine classifier is utilized for mitotic cell modeling and detection.
This method can overcome the difficulty in feature formulation for deformable objects and is independent of tracking or temporal inference model.
The comparison experiments demonstrate that the proposed method can produce competing results with the state-of-the-art methods.
American Psychological Association (APA)
Liu, Anan& Hao, Tong& Gao, Zan& Su, Yuting& Yang, Zhaoxuan. 2013. Nonnegative Mixed-Norm Convex Optimization for Mitotic Cell Detection in Phase Contrast Microscopy. Computational and Mathematical Methods in Medicine،Vol. 2013, no. 2013, pp.1-10.
https://search.emarefa.net/detail/BIM-452022
Modern Language Association (MLA)
Liu, Anan…[et al.]. Nonnegative Mixed-Norm Convex Optimization for Mitotic Cell Detection in Phase Contrast Microscopy. Computational and Mathematical Methods in Medicine No. 2013 (2013), pp.1-10.
https://search.emarefa.net/detail/BIM-452022
American Medical Association (AMA)
Liu, Anan& Hao, Tong& Gao, Zan& Su, Yuting& Yang, Zhaoxuan. Nonnegative Mixed-Norm Convex Optimization for Mitotic Cell Detection in Phase Contrast Microscopy. Computational and Mathematical Methods in Medicine. 2013. Vol. 2013, no. 2013, pp.1-10.
https://search.emarefa.net/detail/BIM-452022
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-452022