Management of Adenovirus in Children after Allogeneic Hematopoietic Stem Cell Transplantation
Joint Authors
Source
Issue
Vol. 2013, Issue 2013 (31 Dec. 2013), pp.1-12, 12 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2013-10-28
Country of Publication
Egypt
No. of Pages
12
Main Subjects
Abstract EN
Adenovirus (ADV) can cause significant morbidity and mortality in children following haematopoietic stem cell transplantation (HSCT), with an incidence of up to 27% and notable associated morbidity and mortality.
T-cell depleted grafts and severe lymphopenia are major risk factors for the development of adenovirus disease after HSCT.
Current antiviral treatments are at best virostatic and may have significant side effects.
Adoptive transfer of donor-derived virus-specific T cells has been shown to be an effective strategy for the prevention and treatment of ADV infection after HSCT.
Here we review progress in the field and present a pathway for the management of adenovirus in the posttransplant setting.
American Psychological Association (APA)
WY Ip, Winnie& Qasim, Waseem. 2013. Management of Adenovirus in Children after Allogeneic Hematopoietic Stem Cell Transplantation. Advances in Hematology،Vol. 2013, no. 2013, pp.1-12.
https://search.emarefa.net/detail/BIM-452039
Modern Language Association (MLA)
WY Ip, Winnie& Qasim, Waseem. Management of Adenovirus in Children after Allogeneic Hematopoietic Stem Cell Transplantation. Advances in Hematology No. 2013 (2013), pp.1-12.
https://search.emarefa.net/detail/BIM-452039
American Medical Association (AMA)
WY Ip, Winnie& Qasim, Waseem. Management of Adenovirus in Children after Allogeneic Hematopoietic Stem Cell Transplantation. Advances in Hematology. 2013. Vol. 2013, no. 2013, pp.1-12.
https://search.emarefa.net/detail/BIM-452039
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-452039