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Detection of Bacillus anthracis Spores Using Peptide Functionalized SERS-Active Substrates
Joint Authors
Sengupta, Atanu
Inscore, Frank
Shende, Chetan
Farquharson, Stuart
Source
International Journal of Spectroscopy
Issue
Vol. 2012, Issue 2012 (31 Dec. 2012), pp.1-6, 6 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2012-10-02
Country of Publication
Egypt
No. of Pages
6
Main Subjects
Abstract EN
The need for portable technologies that can rapidly identify biological warfare agents (BWAs) in the field remains an international priority as expressed at the 2011 Biological Weapons Convention.
In recent years, the ability of surface-enhanced Raman spectroscopy (SERS) to rapidly detect various BWAs at very low concentrations has been demonstrated.
However, in the specific case of Bacillus anthracis, differentiation at the species level is required since other bacilli are common in the environment, representing potential false-positive responses.
To overcome this limitation, we describe the use of a peptide attached to the SERS-active metal that selectively binds Bacillus anthracis-Sterne as the target analyte.
Using this approach, 109 B.
anthracis-Sterne spores/mL produced an intense dipicolinic acid spectrum upon the addition of acetic acid, while the same concentration and treatment of B.
cereus and B.
subtilis did not.
American Psychological Association (APA)
Sengupta, Atanu& Shende, Chetan& Farquharson, Stuart& Inscore, Frank. 2012. Detection of Bacillus anthracis Spores Using Peptide Functionalized SERS-Active Substrates. International Journal of Spectroscopy،Vol. 2012, no. 2012, pp.1-6.
https://search.emarefa.net/detail/BIM-452085
Modern Language Association (MLA)
Sengupta, Atanu…[et al.]. Detection of Bacillus anthracis Spores Using Peptide Functionalized SERS-Active Substrates. International Journal of Spectroscopy No. 2012 (2012), pp.1-6.
https://search.emarefa.net/detail/BIM-452085
American Medical Association (AMA)
Sengupta, Atanu& Shende, Chetan& Farquharson, Stuart& Inscore, Frank. Detection of Bacillus anthracis Spores Using Peptide Functionalized SERS-Active Substrates. International Journal of Spectroscopy. 2012. Vol. 2012, no. 2012, pp.1-6.
https://search.emarefa.net/detail/BIM-452085
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-452085