Bifurcations and Dynamics of Cancer Signaling Network Regulated by MicroRNA
Joint Authors
Source
Discrete Dynamics in Nature and Society
Issue
Vol. 2013, Issue 2013 (31 Dec. 2013), pp.1-7, 7 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2013-12-17
Country of Publication
Egypt
No. of Pages
7
Main Subjects
Abstract EN
MicroRNAs are currently considered as key regulators of a wide variety of biological pathways and regulate many processes of life and obtained more and more attention in recent years.
In this paper, we investigate the dynamics of gene network regulated by miR-34a (microRNA) involved in triple negative feedback loop.
As we know that the p53 network involve in cancer, How the cancer arise is unclear.
We investigate this negative feedback network by using mathematical model and drive the theoretical results of globally asymptotic stability and provide the sufficient conditions for the periodic oscillation.
These results are propitious to understand how p53 network involved in miR-34a induces the cancer.
American Psychological Association (APA)
Zheng, Qianqian& Shen, Jianwei. 2013. Bifurcations and Dynamics of Cancer Signaling Network Regulated by MicroRNA. Discrete Dynamics in Nature and Society،Vol. 2013, no. 2013, pp.1-7.
https://search.emarefa.net/detail/BIM-452099
Modern Language Association (MLA)
Zheng, Qianqian& Shen, Jianwei. Bifurcations and Dynamics of Cancer Signaling Network Regulated by MicroRNA. Discrete Dynamics in Nature and Society No. 2013 (2013), pp.1-7.
https://search.emarefa.net/detail/BIM-452099
American Medical Association (AMA)
Zheng, Qianqian& Shen, Jianwei. Bifurcations and Dynamics of Cancer Signaling Network Regulated by MicroRNA. Discrete Dynamics in Nature and Society. 2013. Vol. 2013, no. 2013, pp.1-7.
https://search.emarefa.net/detail/BIM-452099
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-452099