Effects of Moxa Smoke on Monoamine Neurotransmitters in SAMP8 Mice
Joint Authors
Lim, Min Yee
Guo, Hongzhu
Zhao, Baixiao
Cui, Yingxue
Lao, Lixing
Xu, Huanfang
Liu, Ping
Han, Li
Source
Evidence-Based Complementary and Alternative Medicine
Issue
Vol. 2013, Issue 2013 (31 Dec. 2013), pp.1-6, 6 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2013-05-13
Country of Publication
Egypt
No. of Pages
6
Main Subjects
Abstract EN
Objectives.
To investigate the anti-aging effects of moxa smoke on SAMP8 mice.
Methods.
Using 2×3 factorial design, exposure length (15 or 30 minutes daily), and concentration (low, 5–15 mg/m3; middle, 25–35 mg/m3; high, 85–95 mg/m3), 70 SAMP8 mice were randomly assigned, n=10/group, to a model group or one of six moxa smoke groups: L1, L2, M1, M2, H1, or H2.
Ten SAMR1 mice were used as normal control.
Mice in moxa smoke groups were exposed to moxa smoke at respective concentrations and exposure lengths; the model and normal control mice were not exposed.
Cerebral 5-HT, DA, and NE levels were determined using ELISA.
Results.
Compared to normal control, the model group showed a significant decrease in 5-HT, DA, and NE.
Compared to model group, 5-HT and NE were significantly higher in groups L2, M1, and M2 and DA was significantly so in L2 and M1.
5-HT, DA, and NE levels were the highest in group M1 among moxa smoke groups.
A marked exposure length × concentration interaction was observed for 5-HT, DA, and NE.
Conclusion.
Moxa smoke increases monoamine neurotransmitter levels, which varies according to concentration and exposure length.
Our finding suggests that the middle concentration of moxa smoke for 15 minutes seems the most beneficial.
American Psychological Association (APA)
Xu, Huanfang& Zhao, Baixiao& Cui, Yingxue& Lim, Min Yee& Liu, Ping& Han, Li…[et al.]. 2013. Effects of Moxa Smoke on Monoamine Neurotransmitters in SAMP8 Mice. Evidence-Based Complementary and Alternative Medicine،Vol. 2013, no. 2013, pp.1-6.
https://search.emarefa.net/detail/BIM-452112
Modern Language Association (MLA)
Xu, Huanfang…[et al.]. Effects of Moxa Smoke on Monoamine Neurotransmitters in SAMP8 Mice. Evidence-Based Complementary and Alternative Medicine No. 2013 (2013), pp.1-6.
https://search.emarefa.net/detail/BIM-452112
American Medical Association (AMA)
Xu, Huanfang& Zhao, Baixiao& Cui, Yingxue& Lim, Min Yee& Liu, Ping& Han, Li…[et al.]. Effects of Moxa Smoke on Monoamine Neurotransmitters in SAMP8 Mice. Evidence-Based Complementary and Alternative Medicine. 2013. Vol. 2013, no. 2013, pp.1-6.
https://search.emarefa.net/detail/BIM-452112
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-452112