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Histochemical Evaluation of Human Prostatic Tissues with Cratylia mollis Seed Lectin
Joint Authors
de Lima Bezerra Cavalcanti, Carmelita
Correia, Maria Tereza dos Santos
Silva, Mariana C. C.
Paiva, Patrícia Maria Guedes
Cassandra Breitenbach Barroso Coelho, Luana
Beltrão, Eduardo I. C.
de Lima, Amanda L. R.
Source
Journal of Biomedicine and Biotechnology
Issue
Vol. 2010, Issue 2010 (31 Dec. 2010), pp.1-6, 6 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2010-06-16
Country of Publication
Egypt
No. of Pages
6
Main Subjects
Abstract EN
Lectins, proteins which selectively recognize carbohydrates, have been used in histochemistry for the evaluation of changes in glycosylation in processes of cellular differentiation and/or dedifferentiation.
Cratylia mollis seed lectins (Cramoll 1,4 and Cramoll 3), conjugated to horseradish peroxidase, were used as histochemical probes in human prostate tissues: normal (NP), hyperplasia (BPH), and prostate carcinoma (PCa).
The staining pattern of Con-A and Cramoll 1,4 in BPH was more intense than in NP.
These lectins also showed staining differences between BPH and PCa; the latter showing decreased staining intensity with an increased degree of malignancy.
PNA and Cramoll 3 stained epithelial cells similarly in all diagnoses although they did present intense staining of PCa glands lumen.
Corpora amylacea were not differentially recognized by any of the lectins.
Cramoll 1,4 and Cramoll 3 seed lectins present themselves as candidates for histochemical probes for prostate pathologies when compared to commercial lectins such as Con-A and PNA.
American Psychological Association (APA)
de Lima, Amanda L. R.& de Lima Bezerra Cavalcanti, Carmelita& Silva, Mariana C. C.& Paiva, Patrícia Maria Guedes& Cassandra Breitenbach Barroso Coelho, Luana& Beltrão, Eduardo I. C.…[et al.]. 2010. Histochemical Evaluation of Human Prostatic Tissues with Cratylia mollis Seed Lectin. Journal of Biomedicine and Biotechnology،Vol. 2010, no. 2010, pp.1-6.
https://search.emarefa.net/detail/BIM-452268
Modern Language Association (MLA)
de Lima, Amanda L. R.…[et al.]. Histochemical Evaluation of Human Prostatic Tissues with Cratylia mollis Seed Lectin. Journal of Biomedicine and Biotechnology No. 2010 (2010), pp.1-6.
https://search.emarefa.net/detail/BIM-452268
American Medical Association (AMA)
de Lima, Amanda L. R.& de Lima Bezerra Cavalcanti, Carmelita& Silva, Mariana C. C.& Paiva, Patrícia Maria Guedes& Cassandra Breitenbach Barroso Coelho, Luana& Beltrão, Eduardo I. C.…[et al.]. Histochemical Evaluation of Human Prostatic Tissues with Cratylia mollis Seed Lectin. Journal of Biomedicine and Biotechnology. 2010. Vol. 2010, no. 2010, pp.1-6.
https://search.emarefa.net/detail/BIM-452268
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-452268