Iron (FeII) Chelation, Ferric Reducing Antioxidant Power, and Immune Modulating Potential of Arisaema jacquemontii (Himalayan Cobra Lily)
Joint Authors
Bhagat, Madhulika
Sudan, Rasleen
Gupta, Sahil
Singh, Jasvinder
Koul, Anupurna
Source
Issue
Vol. 2014, Issue 2014 (31 Dec. 2014), pp.1-7, 7 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2014-05-06
Country of Publication
Egypt
No. of Pages
7
Main Subjects
Abstract EN
This study explored the antioxidant and immunomodulatory potential of ethnomedicinally valuable species, namely, Arisaema jacquemontii of north-western Himalayan region.
The tubers, leaves, and fruits of this plant were subjected to extraction using different solvents.
In vitro antioxidant studies were performed in terms of chelation power on ferrous ions and FRAP assay.
The crude methanol extract of leaves was found to harbour better chelating capacity (58% at 100 μg/mL) and reducing power (FRAP value 1085.4±0.11 μMFe3+/g dry wt.) than all the other extracts.
The crude methanol extract was thus further partitioned with solvents to yield five fractions.
Antioxidant study of fractions suggested that the methanol fraction possessed significant chelation capacity (49.7% at 100 μg/mL) and reducing power with FRAP value of 1435.4 μM/g dry wt.
The fractions were also studied for immune modulating potential where it was observed that hexane fraction had significant suppressive effect on mitogen induced T-cell and B-cell proliferation and remarkable stimulating effect on humoral response by 141% and on DTH response by 168% in immune suppressed mice as compared to the controls.
Therefore, it can be concluded that A.
jacquemontii leaves hold considerable antioxidant and immunomodulating potential and they can be explored further for the identification of their chemical composition for a better understanding of their biological activities.
American Psychological Association (APA)
Sudan, Rasleen& Bhagat, Madhulika& Gupta, Sahil& Singh, Jasvinder& Koul, Anupurna. 2014. Iron (FeII) Chelation, Ferric Reducing Antioxidant Power, and Immune Modulating Potential of Arisaema jacquemontii (Himalayan Cobra Lily). BioMed Research International،Vol. 2014, no. 2014, pp.1-7.
https://search.emarefa.net/detail/BIM-452278
Modern Language Association (MLA)
Sudan, Rasleen…[et al.]. Iron (FeII) Chelation, Ferric Reducing Antioxidant Power, and Immune Modulating Potential of Arisaema jacquemontii (Himalayan Cobra Lily). BioMed Research International No. 2014 (2014), pp.1-7.
https://search.emarefa.net/detail/BIM-452278
American Medical Association (AMA)
Sudan, Rasleen& Bhagat, Madhulika& Gupta, Sahil& Singh, Jasvinder& Koul, Anupurna. Iron (FeII) Chelation, Ferric Reducing Antioxidant Power, and Immune Modulating Potential of Arisaema jacquemontii (Himalayan Cobra Lily). BioMed Research International. 2014. Vol. 2014, no. 2014, pp.1-7.
https://search.emarefa.net/detail/BIM-452278
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-452278