Arenavirus Budding
Joint Authors
Urata, Shuzo
de la Torre, Juan Carlos
Source
Issue
Vol. 2011, Issue 2011 (31 Dec. 2011), pp.1-9, 9 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2011-09-08
Country of Publication
Egypt
No. of Pages
9
Main Subjects
Abstract EN
Several arenaviruses cause hemorrhagic fever disease in humans and pose a significant public health concern in their endemic regions.
On the other hand, the prototypic arenavirus LCMV is a superb workhorse for the investigation of virus-host interactions and associated disease.
The arenavirus small RING finger protein called Z has been shown to be the main driving force of virus budding.
The budding activity of Z is mediated by late (L) domain motifs, PT/SAP, and PPXY, located at the C-terminus of Z.
This paper will present the current knowledge on arenavirus budding including the diversity of L domain motifs used by different arenaviruses.
We will also discuss how improved knowledge of arenavirus budding may facilitate the development of novel antiviral strategies to combat human pathogenic arenaviruses.
American Psychological Association (APA)
Urata, Shuzo& de la Torre, Juan Carlos. 2011. Arenavirus Budding. Advances in Virology،Vol. 2011, no. 2011, pp.1-9.
https://search.emarefa.net/detail/BIM-452309
Modern Language Association (MLA)
Urata, Shuzo& de la Torre, Juan Carlos. Arenavirus Budding. Advances in Virology No. 2011 (2011), pp.1-9.
https://search.emarefa.net/detail/BIM-452309
American Medical Association (AMA)
Urata, Shuzo& de la Torre, Juan Carlos. Arenavirus Budding. Advances in Virology. 2011. Vol. 2011, no. 2011, pp.1-9.
https://search.emarefa.net/detail/BIM-452309
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-452309