Surgery Should Complement Endocrine Therapy for Elderly Postmenopausal Women with Hormone Receptor-Positive Early-Stage Breast Cancer
Joint Authors
Leclerc, Yves E.
Leblanc, Guy
Nguyen, Olivier
Gagnon, Marie-Claude
Mitchell, Andrew
Dubé, Pierre
Drolet, Pierre
Sideris, Lucas
Source
International Journal of Surgical Oncology
Issue
Vol. 2012, Issue 2012 (31 Dec. 2012), pp.1-5, 5 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2012-08-27
Country of Publication
Egypt
No. of Pages
5
Main Subjects
Abstract EN
Introduction.
Endocrine therapy (ET) is an integral part of breast cancer (BC) treatment with surgical resection remaining the cornerstone of curative treatment.
The objective of this study is to compare the survival of elderly postmenopausal women with hormone receptor-positive early-stage BC treated with ET alone, without radiation or chemotherapy, versus ET plus surgery.
Materials and Methods.
This is a retrospective study based on a prospective database.
The medical records of postmenopausal BC patients referred to the surgical oncology service of two hospitals during an 8-year period were reviewed.
All patients were to receive ET for a minimum of four months before undergoing any surgery.
Results.
Fifty-one patients were included and divided in two groups, ET alone and ET plus surgery.
At last follow-up in exclusive ET patients (n=28), 39% had stable disease or complete response, 22% had progressive disease, of which 18% died of breast cancer, and 39% died of other causes.
In surgical patients (n=23), 78% were disease-free, 9% died of recurrent breast cancer, and 13% died of other causes.
Conclusions.
These results suggest that surgical resection is beneficial in this group and should be considered, even for patients previously deemed ineligible for surgery.
American Psychological Association (APA)
Nguyen, Olivier& Sideris, Lucas& Drolet, Pierre& Gagnon, Marie-Claude& Leblanc, Guy& Leclerc, Yves E.…[et al.]. 2012. Surgery Should Complement Endocrine Therapy for Elderly Postmenopausal Women with Hormone Receptor-Positive Early-Stage Breast Cancer. International Journal of Surgical Oncology،Vol. 2012, no. 2012, pp.1-5.
https://search.emarefa.net/detail/BIM-452332
Modern Language Association (MLA)
Nguyen, Olivier…[et al.]. Surgery Should Complement Endocrine Therapy for Elderly Postmenopausal Women with Hormone Receptor-Positive Early-Stage Breast Cancer. International Journal of Surgical Oncology No. 2012 (2012), pp.1-5.
https://search.emarefa.net/detail/BIM-452332
American Medical Association (AMA)
Nguyen, Olivier& Sideris, Lucas& Drolet, Pierre& Gagnon, Marie-Claude& Leblanc, Guy& Leclerc, Yves E.…[et al.]. Surgery Should Complement Endocrine Therapy for Elderly Postmenopausal Women with Hormone Receptor-Positive Early-Stage Breast Cancer. International Journal of Surgical Oncology. 2012. Vol. 2012, no. 2012, pp.1-5.
https://search.emarefa.net/detail/BIM-452332
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-452332