Nigella sativa Oil Enhances the Spatial Working Memory Performance of Rats on a Radial Arm Maze
Joint Authors
Sahak, Mohamad Khairul Azali
Hashim, Noor Hashida
Mohamed, Abdul Majid
Hasan Adli, Durriyyah Sharifah
Source
Evidence-Based Complementary and Alternative Medicine
Issue
Vol. 2013, Issue 2013 (31 Dec. 2013), pp.1-5, 5 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2013-12-26
Country of Publication
Egypt
No. of Pages
5
Main Subjects
Abstract EN
Nigella sativa, an established historical and religion-based remedy for a wide range of health problems, is a herbal medicine known to have antioxidant and neuroprotective effects.
This present study investigated the effect of Nigella sativa oil (NSO) administration on the spatial memory performance (SMP) of male adult rats using eight-arm radial arm maze (RAM).
Twelve Sprague Dawley rats (7–9 weeks old) were force-fed daily with 6.0 μL/100 g body weight of Nigella sativa oil (NSO group; n=6) or 0.1 mL/100 g body weight of corn oil (control) (CO group; n=6) for a period of 20 consecutive weeks.
For each weekly evaluation of SMP, one day food-deprived rats were tested by allowing each of them 3 minutes to explore the RAM for food as their rewards.
Similar to the control group, the SMP of the treated group was not hindered, as indicated by the establishment of the reference and working memory components of the spatial memory.
The results demonstrated that lesser mean numbers of error were observed for the NSO-treated group in both parameters as compared to the CO-treated group.
NSO could therefore enhance the learning and memory abilities of the rats; there was a significant decrease in the overall mean number of working memory error (WME) in the NSO-treated group.
American Psychological Association (APA)
Sahak, Mohamad Khairul Azali& Mohamed, Abdul Majid& Hashim, Noor Hashida& Hasan Adli, Durriyyah Sharifah. 2013. Nigella sativa Oil Enhances the Spatial Working Memory Performance of Rats on a Radial Arm Maze. Evidence-Based Complementary and Alternative Medicine،Vol. 2013, no. 2013, pp.1-5.
https://search.emarefa.net/detail/BIM-452335
Modern Language Association (MLA)
Sahak, Mohamad Khairul Azali…[et al.]. Nigella sativa Oil Enhances the Spatial Working Memory Performance of Rats on a Radial Arm Maze. Evidence-Based Complementary and Alternative Medicine No. 2013 (2013), pp.1-5.
https://search.emarefa.net/detail/BIM-452335
American Medical Association (AMA)
Sahak, Mohamad Khairul Azali& Mohamed, Abdul Majid& Hashim, Noor Hashida& Hasan Adli, Durriyyah Sharifah. Nigella sativa Oil Enhances the Spatial Working Memory Performance of Rats on a Radial Arm Maze. Evidence-Based Complementary and Alternative Medicine. 2013. Vol. 2013, no. 2013, pp.1-5.
https://search.emarefa.net/detail/BIM-452335
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-452335