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Current Status and Advances in Quantitative Proteomic Mass Spectrometry
Joint Authors
Wasinger, Valerie C.
Zeng, Ming
Yau, Yunki
Source
International Journal of Proteomics
Issue
Vol. 2013, Issue 2013 (31 Dec. 2013), pp.1-12, 12 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2013-03-06
Country of Publication
Egypt
No. of Pages
12
Main Subjects
Topics
Abstract EN
The accurate quantitation of proteins and peptides in complex biological systems is one of the most challenging areas of proteomics.
Mass spectrometry-based approaches have forged significant in-roads allowing accurate and sensitive quantitation and the ability to multiplex vastly complex samples through the application of robust bioinformatic tools.
These relative and absolute quantitative measures using label-free, tags, or stable isotope labelling have their own strengths and limitations.
The continuous development of these methods is vital for increasing reproducibility in the rapidly expanding application of quantitative proteomics in biomarker discovery and validation.
This paper provides a critical overview of the primary mass spectrometry-based quantitative approaches and the current status of quantitative proteomics in biomedical research.
American Psychological Association (APA)
Wasinger, Valerie C.& Zeng, Ming& Yau, Yunki. 2013. Current Status and Advances in Quantitative Proteomic Mass Spectrometry. International Journal of Proteomics،Vol. 2013, no. 2013, pp.1-12.
https://search.emarefa.net/detail/BIM-452337
Modern Language Association (MLA)
Wasinger, Valerie C.…[et al.]. Current Status and Advances in Quantitative Proteomic Mass Spectrometry. International Journal of Proteomics No. 2013 (2013), pp.1-12.
https://search.emarefa.net/detail/BIM-452337
American Medical Association (AMA)
Wasinger, Valerie C.& Zeng, Ming& Yau, Yunki. Current Status and Advances in Quantitative Proteomic Mass Spectrometry. International Journal of Proteomics. 2013. Vol. 2013, no. 2013, pp.1-12.
https://search.emarefa.net/detail/BIM-452337
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-452337