Leprosy : An Overview of Pathophysiology
Joint Authors
Bhat, Ramesh Marne
Prakash, Chaitra
Source
Interdisciplinary Perspectives on Infectious Diseases
Issue
Vol. 2012, Issue 2012 (31 Dec. 2012), pp.1-6, 6 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2012-09-04
Country of Publication
Egypt
No. of Pages
6
Main Subjects
Abstract EN
Leprosy, also known as Hansen’s disease, is a chronic infectious disease caused by Mycobacterium leprae, a microorganism that has a predilection for the skin and nerves.
The disease is clinically characterized by one or more of the three cardinal signs: hypopigmented or erythematous skin patches with definite loss of sensation, thickened peripheral nerves, and acid-fast bacilli detected on skin smears or biopsy material.
M.
leprae primarily infects Schwann cells in the peripheral nerves leading to nerve damage and the development of disabilities.
Despite reduced prevalence of M.
leprae infection in the endemic countries following implementation of multidrug therapy (MDT) program by WHO to treat leprosy, new case detection rates are still high-indicating active transmission.
The susceptibility to the mycobacteria and the clinical course of the disease are attributed to the host immune response, which heralds the review of immunopathology of this complex disease.
American Psychological Association (APA)
Bhat, Ramesh Marne& Prakash, Chaitra. 2012. Leprosy : An Overview of Pathophysiology. Interdisciplinary Perspectives on Infectious Diseases،Vol. 2012, no. 2012, pp.1-6.
https://search.emarefa.net/detail/BIM-452400
Modern Language Association (MLA)
Bhat, Ramesh Marne& Prakash, Chaitra. Leprosy : An Overview of Pathophysiology. Interdisciplinary Perspectives on Infectious Diseases No. 2012 (2012), pp.1-6.
https://search.emarefa.net/detail/BIM-452400
American Medical Association (AMA)
Bhat, Ramesh Marne& Prakash, Chaitra. Leprosy : An Overview of Pathophysiology. Interdisciplinary Perspectives on Infectious Diseases. 2012. Vol. 2012, no. 2012, pp.1-6.
https://search.emarefa.net/detail/BIM-452400
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-452400