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Effects of a Commercial Canine Gonadotropin Releasing Hormone Vaccination on Intact Male Llamas and Alpacas
Joint Authors
Bobe, G.
Patton, K. M.
Kutzler, Michelle
Grossman, J. L.
Donovan, C. E.
Lamb, S.
Source
Issue
Vol. 2013, Issue 2013 (31 Dec. 2013), pp.1-7, 7 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2013-03-17
Country of Publication
Egypt
No. of Pages
7
Main Subjects
Abstract EN
We have investigated the effect of immunization against gonadotropin releasing hormone (GnRH) using a commercial canine GnRH vaccine on testosterone concentration, testicular volume, testicular histology, and intermale behavior in intact male llamas and alpacas.
Llamas (n=28) and alpacas (n=20) were either immunized (received 3 mL of vaccine given intramuscularly) or treated as controls (received 3 mL of sterile diluent given intramuscularly) at 0, 3, and 6 weeks.
Blood samples and testicular volume measurements were taken at 0, 3, 6, 9, and 12 weeks.
Owner surveys grading behavior at 0 and 12 weeks were received for 14 llamas.
Two llamas at each time point undergoing the vaccination procedure were also castrated for testicular histological examination.
Vaccinated animals elicited a GnRH antibody titer, and there was a significant decrease in testosterone concentration and testicular volume when compared with control animals.
Intermale aggressive behavior was also significantly decreased in the surveyed llamas.
However, histological examination revealed no significant changes.
GnRH immunization using the canine GnRH vaccine may be an effective method for reducing intermale aggression in llamas and alpacas by decreasing circulating testosterone concentrations but cannot be recommended as an immunosterilant because of its lack of efficacy in interrupting spermatogenesis.
American Psychological Association (APA)
Donovan, C. E.& Grossman, J. L.& Patton, K. M.& Lamb, S.& Bobe, G.& Kutzler, Michelle. 2013. Effects of a Commercial Canine Gonadotropin Releasing Hormone Vaccination on Intact Male Llamas and Alpacas. Journal of Vaccines،Vol. 2013, no. 2013, pp.1-7.
https://search.emarefa.net/detail/BIM-452454
Modern Language Association (MLA)
Donovan, C. E.…[et al.]. Effects of a Commercial Canine Gonadotropin Releasing Hormone Vaccination on Intact Male Llamas and Alpacas. Journal of Vaccines No. 2013 (2013), pp.1-7.
https://search.emarefa.net/detail/BIM-452454
American Medical Association (AMA)
Donovan, C. E.& Grossman, J. L.& Patton, K. M.& Lamb, S.& Bobe, G.& Kutzler, Michelle. Effects of a Commercial Canine Gonadotropin Releasing Hormone Vaccination on Intact Male Llamas and Alpacas. Journal of Vaccines. 2013. Vol. 2013, no. 2013, pp.1-7.
https://search.emarefa.net/detail/BIM-452454
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-452454