Network Properties for Ranking Predicted miRNA Targets in Breast Cancer
Joint Authors
Olsson, Björn
Lubovac, Zelmina
Linde, Jörg
Source
Issue
Vol. 2009, Issue 2009 (31 Dec. 2009), pp.1-7, 7 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2010-03-07
Country of Publication
Egypt
No. of Pages
7
Main Subjects
Natural & Life Sciences (Multidisciplinary)
Biology
Abstract EN
MicroRNAs control the expression of their target genes by translational repression and transcriptional cleavage.
They are involved in various biological processes including development and progression of cancer.
To uncover the biological role of miRNAs it is important to identify their target genes.
The small number of experimentally validated target genes makes computer prediction methods very important.
However, state-of-the-art prediction tools result in a great number of putative targets with an unpredictable number of false positives.
In this paper, we propose and evaluate two approaches for ranking the biological relevance of putative targets of miRNAs which are associated with breast cancer.
American Psychological Association (APA)
Linde, Jörg& Olsson, Björn& Lubovac, Zelmina. 2010. Network Properties for Ranking Predicted miRNA Targets in Breast Cancer. Advances in Bioinformatics،Vol. 2009, no. 2009, pp.1-7.
https://search.emarefa.net/detail/BIM-452525
Modern Language Association (MLA)
Linde, Jörg…[et al.]. Network Properties for Ranking Predicted miRNA Targets in Breast Cancer. Advances in Bioinformatics No. 2009 (2009), pp.1-7.
https://search.emarefa.net/detail/BIM-452525
American Medical Association (AMA)
Linde, Jörg& Olsson, Björn& Lubovac, Zelmina. Network Properties for Ranking Predicted miRNA Targets in Breast Cancer. Advances in Bioinformatics. 2010. Vol. 2009, no. 2009, pp.1-7.
https://search.emarefa.net/detail/BIM-452525
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-452525