Reticulophagy and Ribophagy : Regulated Degradation of Protein Production Factories
Joint Authors
Reggiori, Fulvio
Kraft, Claudine
Cebollero, Eduardo
Source
International Journal of Cell Biology
Issue
Vol. 2012, Issue 2012 (31 Dec. 2012), pp.1-9, 9 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2012-02-28
Country of Publication
Egypt
No. of Pages
9
Main Subjects
Abstract EN
During autophagy, cytosol, protein aggregates, and organelles are sequestered into double-membrane vesicles called autophagosomes and delivered to the lysosome/vacuole for breakdown and recycling of their basic components.
In all eukaryotes this pathway is important for adaptation to stress conditions such as nutrient deprivation, as well as to regulate intracellular homeostasis by adjusting organelle number and clearing damaged structures.
For a long time, starvation-induced autophagy has been viewed as a nonselective transport pathway; however, recent studies have revealed that autophagy is able to selectively engulf specific structures, ranging from proteins to entire organelles.
In this paper, we discuss recent findings on the mechanisms and physiological implications of two selective types of autophagy: ribophagy, the specific degradation of ribosomes, and reticulophagy, the selective elimination of portions of the ER.
American Psychological Association (APA)
Cebollero, Eduardo& Reggiori, Fulvio& Kraft, Claudine. 2012. Reticulophagy and Ribophagy : Regulated Degradation of Protein Production Factories. International Journal of Cell Biology،Vol. 2012, no. 2012, pp.1-9.
https://search.emarefa.net/detail/BIM-452538
Modern Language Association (MLA)
Cebollero, Eduardo…[et al.]. Reticulophagy and Ribophagy : Regulated Degradation of Protein Production Factories. International Journal of Cell Biology No. 2012 (2012), pp.1-9.
https://search.emarefa.net/detail/BIM-452538
American Medical Association (AMA)
Cebollero, Eduardo& Reggiori, Fulvio& Kraft, Claudine. Reticulophagy and Ribophagy : Regulated Degradation of Protein Production Factories. International Journal of Cell Biology. 2012. Vol. 2012, no. 2012, pp.1-9.
https://search.emarefa.net/detail/BIM-452538
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-452538