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Neuroleptic Malignant Syndrome Caused by a Combination of Carbamazepine and Amitriptyline
Joint Authors
Osman, Aboubaker
Janati, A. Bruce
ALGhasab, Naif Saad
Source
Case Reports in Neurological Medicine
Issue
Vol. 2012, Issue 2012 (31 Dec. 2012), pp.1-3, 3 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2012-07-24
Country of Publication
Egypt
No. of Pages
3
Main Subjects
Abstract EN
A 32-year-old female, with a history of secondarily-generalized convulsive epilepsy, mental retardation, and a psychiatric illness, developed neuroleptic malignant syndrome while receiving carbamazepine and amitriptyline concurrently.
We hypothesize that the addition of amitriptyline to carbamazepine caused a decrease in the serum level of carbamazepine, resulting in NMS.
We conclude that combination therapy with carbamazepine and amitriptyline should be avoided in patients who are predisposed to NMS.
The purpose of this paper is to warn physicians against combination therapy with carbamazepine and tricyclic antidepressants which may be conducive to neuroleptic malignant syndrome in susceptible patients.
American Psychological Association (APA)
Janati, A. Bruce& ALGhasab, Naif Saad& Osman, Aboubaker. 2012. Neuroleptic Malignant Syndrome Caused by a Combination of Carbamazepine and Amitriptyline. Case Reports in Neurological Medicine،Vol. 2012, no. 2012, pp.1-3.
https://search.emarefa.net/detail/BIM-452581
Modern Language Association (MLA)
Janati, A. Bruce…[et al.]. Neuroleptic Malignant Syndrome Caused by a Combination of Carbamazepine and Amitriptyline. Case Reports in Neurological Medicine No. 2012 (2012), pp.1-3.
https://search.emarefa.net/detail/BIM-452581
American Medical Association (AMA)
Janati, A. Bruce& ALGhasab, Naif Saad& Osman, Aboubaker. Neuroleptic Malignant Syndrome Caused by a Combination of Carbamazepine and Amitriptyline. Case Reports in Neurological Medicine. 2012. Vol. 2012, no. 2012, pp.1-3.
https://search.emarefa.net/detail/BIM-452581
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-452581