Differentiated Thyroid Cancer with Extrathyroidal Extension : Prognosis and the Role of External Beam Radiotherapy
Joint Authors
Panzarella, Tony
Brierley, James D.
Sia, Michael A.
Tsang, Richard W.
Source
Issue
Vol. 2010, Issue 2010 (31 Dec. 2010), pp.1-7, 7 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2010-05-06
Country of Publication
Egypt
No. of Pages
7
Main Subjects
Abstract EN
A study was performed to identify variables that affected cause-specific survival (CSS) and local relapse-free rate (LRFR) in patients with differentiated thyroid cancer (DTC) and extrathyroid extension (ETE) and to examine the role of external beam radiotherapy (XRT).
Prognostic factors were similar to those found in studies of all patients with DTC.
In patients with postoperative gross residual disease treated with radiotherapy, 10-year CSS and LRFR were 48% and 90%.
For patients with no residual or microscopic disease, 10-year CSS and LRFR were 92% and 93%.
In patients older than 60 years with T3 ETE but no gross residual disease postoperatively there was an improved LRFR at 5 years of 96%, compared to 87.5% without XRT (P=.02).
Patients with gross ETE benefit from XRT and there may be a potential benefit in reducing locoregional failure in patients over 60 years with minimal extrathyroidal extension (T3).
American Psychological Association (APA)
Sia, Michael A.& Tsang, Richard W.& Panzarella, Tony& Brierley, James D.. 2010. Differentiated Thyroid Cancer with Extrathyroidal Extension : Prognosis and the Role of External Beam Radiotherapy. Journal of Thyroid Research،Vol. 2010, no. 2010, pp.1-7.
https://search.emarefa.net/detail/BIM-452594
Modern Language Association (MLA)
Sia, Michael A.…[et al.]. Differentiated Thyroid Cancer with Extrathyroidal Extension : Prognosis and the Role of External Beam Radiotherapy. Journal of Thyroid Research No. 2010 (2010), pp.1-7.
https://search.emarefa.net/detail/BIM-452594
American Medical Association (AMA)
Sia, Michael A.& Tsang, Richard W.& Panzarella, Tony& Brierley, James D.. Differentiated Thyroid Cancer with Extrathyroidal Extension : Prognosis and the Role of External Beam Radiotherapy. Journal of Thyroid Research. 2010. Vol. 2010, no. 2010, pp.1-7.
https://search.emarefa.net/detail/BIM-452594
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-452594