Topical Application Effect of the Isolectin Hydrogel (Cramoll 1,4) on Second-Degree Burns : Experimental Model
Joint Authors
dos Anjos Carneiro-Leão, Ana Maria
dos Santos Correia, Maria Tereza
de Lima Bezerra Cavalcanti, Carmelita
Cassandra Breitenbach Barroso Coelho, Luana
Santos-Oliveira, Ralph
dos Santos Tavares Pereira, Danielle
de Pontes-Filho, Nicodemos Teles
Madruga Lima-Ribeiro, Maria Helena
Source
Journal of Biomedicine and Biotechnology
Issue
Vol. 2012, Issue 2012 (31 Dec. 2012), pp.1-11, 11 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2012-02-14
Country of Publication
Egypt
No. of Pages
11
Main Subjects
Abstract EN
This study aimed at evaluating the use of hydrogel isolectin in the treatment of second-degree burns.
Twenty male rats were randomly divided into two groups (G1 = treatment with hydrogel containing 100 μg/mL Cramoll 1,4 and G2 = Control, hydrogel).
After 7, 14, 21, 28, and 35 days, animals were euthanized.
On the 7th day, G1 showed intense exudates, necrosis and edema.
On the 14th day, G1 showed tissue reepithelialization and moderate autolysis.
On the 21st day, G1 showed intense fibroblastic proliferation, presence of dense collagen, and moderate fibrosis.
On the 28th day, G1 showed complete tissue epithelialization.
On the 35th day, G1 showed modeled dense collagen.
The significant wound contraction was initiated from day, 14 in the G1.
There were no significant differences in biochemical and hematological parameters analyzed.
These results extend the potential of therapeutic applications for Cramoll 1,4 in the treatment of thermal burns.
American Psychological Association (APA)
dos Santos Tavares Pereira, Danielle& Madruga Lima-Ribeiro, Maria Helena& Santos-Oliveira, Ralph& de Lima Bezerra Cavalcanti, Carmelita& de Pontes-Filho, Nicodemos Teles& Cassandra Breitenbach Barroso Coelho, Luana…[et al.]. 2012. Topical Application Effect of the Isolectin Hydrogel (Cramoll 1,4) on Second-Degree Burns : Experimental Model. Journal of Biomedicine and Biotechnology،Vol. 2012, no. 2012, pp.1-11.
https://search.emarefa.net/detail/BIM-452693
Modern Language Association (MLA)
dos Santos Tavares Pereira, Danielle…[et al.]. Topical Application Effect of the Isolectin Hydrogel (Cramoll 1,4) on Second-Degree Burns : Experimental Model. Journal of Biomedicine and Biotechnology No. 2012 (2012), pp.1-11.
https://search.emarefa.net/detail/BIM-452693
American Medical Association (AMA)
dos Santos Tavares Pereira, Danielle& Madruga Lima-Ribeiro, Maria Helena& Santos-Oliveira, Ralph& de Lima Bezerra Cavalcanti, Carmelita& de Pontes-Filho, Nicodemos Teles& Cassandra Breitenbach Barroso Coelho, Luana…[et al.]. Topical Application Effect of the Isolectin Hydrogel (Cramoll 1,4) on Second-Degree Burns : Experimental Model. Journal of Biomedicine and Biotechnology. 2012. Vol. 2012, no. 2012, pp.1-11.
https://search.emarefa.net/detail/BIM-452693
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-452693