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Performance of Routine Helicobacter pylori Invasive Tests in Patients with Dyspepsia
Joint Authors
Lee, Hsi-Chang
Wang, Chung-Kwe
Lin, Chin-Lin
Huang, Ting-Chang
Chen, Kuan-Yang
Wu, Deng-Chyang
Source
Gastroenterology Research and Practice
Issue
Vol. 2013, Issue 2013 (31 Dec. 2013), pp.1-5, 5 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2013-12-18
Country of Publication
Egypt
No. of Pages
5
Main Subjects
Abstract EN
Background.
This study was designed to compare the accuracy of three different invasive methods for the detection of Helicobacter pylori (H.
pylori) infection in patients with dyspepsia.
These tests included culture, histology, and the rapid urease test (CLO test).
Methods.
H.
pylori infection was diagnosed prospectively in 246 untreated dyspeptic patients who underwent upper gastrointestinal endoscopy.
The gold standard for H.
pylori infection was based on a positive culture or both a positive histological examination and a CLO test.
Results.
H.
pylori was diagnosed in 33.3% of the patients.
The sensitivity, specificity, positive predictive value, negative predictive value, and overall accuracy were as follows: histology from the antrum (95.12; 95.12; 90.7; 97.5; 95.12%); histology from the antrum and corpus (95.12; 95.12; 90.7; 97.5; 95.12%); histology from the corpus (76.83; 96.95; 92.65; 89.33; 90.24%); culture (91.46; 100; 100; 95.91; 97.15%); a CLO test from the antrum and corpus (85.59; 100; 100; 93.71; 95.52%); a CLO test from the antrum (64.63; 100; 100; 84.97; 88.21%); a CLO test from the corpus (69.51; 100; 100; 96.77; 89.83%), respectively.
Conclusions.
Antral biopsy histology and culture are the best methods for the diagnosis of H.
pylori infection in our cohort of patients with dyspepsia.
American Psychological Association (APA)
Lee, Hsi-Chang& Huang, Ting-Chang& Lin, Chin-Lin& Chen, Kuan-Yang& Wang, Chung-Kwe& Wu, Deng-Chyang. 2013. Performance of Routine Helicobacter pylori Invasive Tests in Patients with Dyspepsia. Gastroenterology Research and Practice،Vol. 2013, no. 2013, pp.1-5.
https://search.emarefa.net/detail/BIM-452717
Modern Language Association (MLA)
Lee, Hsi-Chang…[et al.]. Performance of Routine Helicobacter pylori Invasive Tests in Patients with Dyspepsia. Gastroenterology Research and Practice No. 2013 (2013), pp.1-5.
https://search.emarefa.net/detail/BIM-452717
American Medical Association (AMA)
Lee, Hsi-Chang& Huang, Ting-Chang& Lin, Chin-Lin& Chen, Kuan-Yang& Wang, Chung-Kwe& Wu, Deng-Chyang. Performance of Routine Helicobacter pylori Invasive Tests in Patients with Dyspepsia. Gastroenterology Research and Practice. 2013. Vol. 2013, no. 2013, pp.1-5.
https://search.emarefa.net/detail/BIM-452717
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-452717