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Accuracy of D-Dimers to Rule Out Venous Thromboembolism Events across Age Categories
Joint Authors
Der Sahakian, G.
Allo, J. C.
Kansao, J.
Kierzek, G.
Claessens, Y. E.
Pourriat, J. L.
Source
Emergency Medicine International
Issue
Vol. 2010, Issue 2010 (31 Dec. 2010), pp.1-4, 4 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2010-07-27
Country of Publication
Egypt
No. of Pages
4
Main Subjects
Abstract EN
Background.
Strategies combining pretest clinical assessment and D-dimers measurement efficiently and safely rule out venous thromboembolism events (VTE) in low- and intermediate-risk patients.
Objectives.
As process of ageing is associated with altered concentrations of coagulation markers including an increase in D-dimers levels, we investigated whether D-dimers could reliably rule out VTE across age categories.
Method.
We prospectively assessed the test performance in 1,004 patients visiting the emergency department during the 6-month period with low or intermediate risk of VTE who also received additional diagnostic procedures.
Results.
67 patients had VTE with D-dimers levels above the threshold, and 3 patients displayed D-dimers levels below the threshold.
We observed that specificity of D-dimers test decreased in an age-dependent manner.
However, sensitivity and negative predictive value remained at very high level in each age category including older patients.
Conclusion.
We conclude that, even though D-dimers level could provide numerous false positive results in elderly patients, its high sensitivity could reliably help physicians to exclude the diagnosis of VTE in every low- and intermediate-risk patient.
American Psychological Association (APA)
Der Sahakian, G.& Claessens, Y. E.& Allo, J. C.& Kansao, J.& Kierzek, G.& Pourriat, J. L.. 2010. Accuracy of D-Dimers to Rule Out Venous Thromboembolism Events across Age Categories. Emergency Medicine International،Vol. 2010, no. 2010, pp.1-4.
https://search.emarefa.net/detail/BIM-452775
Modern Language Association (MLA)
Der Sahakian, G.…[et al.]. Accuracy of D-Dimers to Rule Out Venous Thromboembolism Events across Age Categories. Emergency Medicine International No. 2010 (2010), pp.1-4.
https://search.emarefa.net/detail/BIM-452775
American Medical Association (AMA)
Der Sahakian, G.& Claessens, Y. E.& Allo, J. C.& Kansao, J.& Kierzek, G.& Pourriat, J. L.. Accuracy of D-Dimers to Rule Out Venous Thromboembolism Events across Age Categories. Emergency Medicine International. 2010. Vol. 2010, no. 2010, pp.1-4.
https://search.emarefa.net/detail/BIM-452775
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-452775