High Efficacy of Preoperative Low-Dose Radiotherapy with Sanazole (AK-2123) for Extraskeletal Ewing's Sarcoma : A Case Report
Joint Authors
Sakabe, Tomoya
Sawai, Yasushi
Kagiya, Tsutomu V.
Horie, Naoyuki
Yamazaki, Hideya
Matsui, Takaaki
Murata, Hiroaki
Kubo, Toshikazu
Konishi, Eiichi
Koto, Kazutaka
Source
Issue
Vol. 2011, Issue 2011 (31 Dec. 2011), pp.1-6, 6 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2010-09-06
Country of Publication
Egypt
No. of Pages
6
Main Subjects
Abstract EN
Extraskeletal Ewing's sarcoma is a rare soft tissue tumor that is morphologically indistinguishable from Ewing's sarcoma of bone.
We report a case of extraskeletal Ewing's sarcoma with several systemic problems.
A 69-year-old man presented with a 5-month history of a rapidly enlarging mass in the right thigh.
Because preoperative radiotherapy with sanazole (AK-2123) contributed the tumor mass reduction down to 40% in size, the tumor was successfully resected with clear surgical margins and repaired with a musculocutaneous flap.
The high efficacy of pre-operative low-dose radiotherapy with sanazole was histologically confirmed that the resected tumor specimen involved no viable tumor cells and showed 100% necrosis.
Based on clinical outcomes in this case, the combined modality of pre-operative low-dose radiotherapy with hypoxic cell radiosensitizer and adequate surgical resection might provide for the useful clinical application of extraskeletal Ewing's sarcoma treatment.
American Psychological Association (APA)
Sakabe, Tomoya& Murata, Hiroaki& Konishi, Eiichi& Koto, Kazutaka& Horie, Naoyuki& Matsui, Takaaki…[et al.]. 2010. High Efficacy of Preoperative Low-Dose Radiotherapy with Sanazole (AK-2123) for Extraskeletal Ewing's Sarcoma : A Case Report. Sarcoma،Vol. 2011, no. 2011, pp.1-6.
https://search.emarefa.net/detail/BIM-452780
Modern Language Association (MLA)
Sakabe, Tomoya…[et al.]. High Efficacy of Preoperative Low-Dose Radiotherapy with Sanazole (AK-2123) for Extraskeletal Ewing's Sarcoma : A Case Report. Sarcoma No. 2011 (2011), pp.1-6.
https://search.emarefa.net/detail/BIM-452780
American Medical Association (AMA)
Sakabe, Tomoya& Murata, Hiroaki& Konishi, Eiichi& Koto, Kazutaka& Horie, Naoyuki& Matsui, Takaaki…[et al.]. High Efficacy of Preoperative Low-Dose Radiotherapy with Sanazole (AK-2123) for Extraskeletal Ewing's Sarcoma : A Case Report. Sarcoma. 2010. Vol. 2011, no. 2011, pp.1-6.
https://search.emarefa.net/detail/BIM-452780
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-452780