Electroanalytical Characterisation of Dopa Decarboxylase Inhibitors Carbidopa and Benserazide on Multiwalled Carbon Nanotube and Poly(Nile blue A) Modified Glassy Carbon Electrodes
Joint Authors
Kul, Dilek
Brett, Christopher M. A.
Source
International Journal of Electrochemistry
Issue
Vol. 2011, Issue 2011 (31 Dec. 2011), pp.1-7, 7 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2011-06-04
Country of Publication
Egypt
No. of Pages
7
Main Subjects
Abstract EN
Modified glassy carbon electrodes have been made by deposition of functionalised multiwalled carbon nanotubes (MWCNTs) followed by formation of poly(Nile blue) (PNB) films by electropolymerisation, using potential cycling in 0.1 M phosphate buffer solution (PBS) at pH 6.0.
The electrochemical oxidation of carbidopa (CD) and benserazide (BS) on these MWCNTs/PNB-modified electrodes was investigated using cyclic and differential pulse voltammetry in 0.1 M PBS at different values of pH between 5.0 and 8.0; both CD and BS gave one diffusion-controlled irreversible oxidation peak in cyclic voltammetry.
Analytical characterisation of CD and BS was carried out in 0.1 M PBS, pH 5.0.
Peak currents in differential pulse voltammetry were linear over the concentration range of 1×10−5 to 1×10−4 M for CD and 4×10−6 to 4×10−5 M for BS.
The repeatability, precision, and accuracy of the method were also investigated.
Higher sensitivities and lower detection limits, of 1.17 μM for CD and 0.50 μM for BS, were obtained with this new modified electrode compared with previous studies reported in the literature.
American Psychological Association (APA)
Kul, Dilek& Brett, Christopher M. A.. 2011. Electroanalytical Characterisation of Dopa Decarboxylase Inhibitors Carbidopa and Benserazide on Multiwalled Carbon Nanotube and Poly(Nile blue A) Modified Glassy Carbon Electrodes. International Journal of Electrochemistry،Vol. 2011, no. 2011, pp.1-7.
https://search.emarefa.net/detail/BIM-452822
Modern Language Association (MLA)
Kul, Dilek& Brett, Christopher M. A.. Electroanalytical Characterisation of Dopa Decarboxylase Inhibitors Carbidopa and Benserazide on Multiwalled Carbon Nanotube and Poly(Nile blue A) Modified Glassy Carbon Electrodes. International Journal of Electrochemistry No. 2011 (2011), pp.1-7.
https://search.emarefa.net/detail/BIM-452822
American Medical Association (AMA)
Kul, Dilek& Brett, Christopher M. A.. Electroanalytical Characterisation of Dopa Decarboxylase Inhibitors Carbidopa and Benserazide on Multiwalled Carbon Nanotube and Poly(Nile blue A) Modified Glassy Carbon Electrodes. International Journal of Electrochemistry. 2011. Vol. 2011, no. 2011, pp.1-7.
https://search.emarefa.net/detail/BIM-452822
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-452822