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Synthesis and Antimicrobial Activity of Some New Thiazolidin-4-one Derivatives of 4-(6-methylbenzo[d]thiazol-2-yl)benzamine
Joint Authors
Hussein, Awaz Jamil
Jalal Azeez, Hashim
Source
Issue
Vol. 2013, Issue 2013 (31 Dec. 2013), pp.1-6, 6 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2012-11-07
Country of Publication
Egypt
No. of Pages
6
Main Subjects
Abstract EN
A number of derivatives of 2-(substituted phenyl)-3-(4-(6-methylbenzo[d]thiazol-2-yl)phenyl) thiazolidin-4-one (3a–j) have been synthesized from the reaction of 4-(6-methylbenzo[d]thiazol-2-yl)benzenamine(1), with different substituted benzaldehydes (2a–j), followed by cyclocondensation reaction of the prepared imines with 2-meraptoacetic acid in high yields.
Furthermore, the structures of the newly synthesized compounds were confirmed by FT-IR, 13C-NMR,13C-DEPT, and 1H-NMR spectral data.
The imines and thiazolidin-4-one derivatives were evaluated for their antibacterial activity against Escherichia coli as gram negative and Staphylococcus aureus as gram positive, the results have shown significant activity against both types of bacteria.
American Psychological Association (APA)
Hussein, Awaz Jamil& Jalal Azeez, Hashim. 2012. Synthesis and Antimicrobial Activity of Some New Thiazolidin-4-one Derivatives of 4-(6-methylbenzo[d]thiazol-2-yl)benzamine. Journal of Chemistry،Vol. 2013, no. 2013, pp.1-6.
https://search.emarefa.net/detail/BIM-452837
Modern Language Association (MLA)
Hussein, Awaz Jamil& Jalal Azeez, Hashim. Synthesis and Antimicrobial Activity of Some New Thiazolidin-4-one Derivatives of 4-(6-methylbenzo[d]thiazol-2-yl)benzamine. Journal of Chemistry No. 2013 (2013), pp.1-6.
https://search.emarefa.net/detail/BIM-452837
American Medical Association (AMA)
Hussein, Awaz Jamil& Jalal Azeez, Hashim. Synthesis and Antimicrobial Activity of Some New Thiazolidin-4-one Derivatives of 4-(6-methylbenzo[d]thiazol-2-yl)benzamine. Journal of Chemistry. 2012. Vol. 2013, no. 2013, pp.1-6.
https://search.emarefa.net/detail/BIM-452837
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-452837